Azifast 250 Tablet

Azifast 250 Tablet is an antibiotic that treats many bacterial infections such as pneumonia, gonorrhoea, pharyngitis, diphtheria, and sinusitis. It contains azithromycin, a broad-spectrum bacteriostatic macrolide antibiotic that stops the growth of infection-causing bacteria. It is often prescribed for infections of the lungs, ears, throat, sinuses, skin and reproductive tract.

Azifast 250 Tablet should be taken as advised by your doctor. It is best to have it after food to prevent side effects. It is recommended that all courses of antibiotic treatment be strictly followed and not prematurely discontinued, irrespective of any perceived relief of symptoms. Try not to miss a dose, and never try to compensate for a missed dose by taking double the dosage.

Side effects of Azifast 250 Tablet are usually minor and should not be of any concern. As it is an antibiotic, gastrointestinal side effects such as stomach pain, diarrhoea and vomiting are common. Your doctor may also prescribe an acidity-regulating medicine (PPIs such as pantoprazole or omeprazole) to counter these adverse effects.

Azifast 250 Tablet may be contraindicated (unsafe) for people with existing or history of heart problems, kidney impairment, liver diseases, hypomagnesemia, hypokalemia or allergies to macrolides antibiotics such as azithromycin, clarithromycin and erythromycin. Always let your doctor know of any health conditions you might have. Generally, this medicine is considered safe for most people.

Azifast 250 Tablet contains a macrolide antibiotic called azithromycin that treats bacterial infections of the lungs, ears, throat, sinuses, skin and reproductive tract.

This medicine may be prescribed for the following infections:

The mechanism of action of Azifast 250 Tablet involves inhibiting the proliferation of harmful bacteria by inhibiting the synthesis of a vital protein necessary for their growth.

Azifast 250 Tablet contains azithromycin, a broad-spectrum bacteriostatic macrolide antibiotic that stops the bacterial growth. To reproduce, bacteria need a precise mechanism for generating proteins, which involves ribosomal proteins 6. However, azithromycin interacts with the 50S ribosomal subunit by attaching to the 23S rRNA.

This interaction disrupts the transpeptidation/translocation phase and the assembly of the 50S ribosomal subunit, which ultimately prevents the production of proteins in the bacteria. As a result, azithromycin effectively controls bacterial infection.

• Azithromycin (medlineplus.gov)
• Azithromycin (accessdata.fda.gov)
• Azithromycin: Drug information (clinicalinfo.hiv.gov)
• Philip Anderson - Handbook of Clinical Drug Data