Alsatinib Tablet

Alsatinib Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

Alsatinib Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

• Blood cancer (Chronic myeloid leukaemia)

Blood cancer (Chronic myeloid leukaemia)
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Alsatinib Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nextki

• Abdominal pain
• Anemia (low number of red blood cells)
• Breathing problems
• Fatigue
• Fever
• Headache
• Infection
• Low blood platelets
• Musculoskeletal (bone, muscle or joint) pain
• Nausea
• Rash
• Vomiting

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Alsatinib Tablet may be taken with or without food, but it is better to take it at a fixed time.

Alsatinib Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

• Take it with or without food, preferably at the same time each day.
• Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
• Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
• Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
• It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
• Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Chabner BA, Barnes J, Neal J, et al. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1732-34.

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 953.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 361-62.

Dasatinib monohydrate. Dublin, Ireland: Bristol-Myers Squibb Pharma; 2006 [revised 06 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:

Drugs.com. Dasatinib Pregnancy and Breastfeeding Warnings. [Accessed 26 Mar. 2019] (online) Available from:

Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Dasatinib. [Updated 2018 Dec 3]. [Accessed 18 Feb. 2020] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from: