Trimetazidine
Introduction To Trimetazidine
Trimetazidine is an anti-anginal medicine used for treating heart-related chest pain (angina). It prevents new attacks of angina but does not stop an acute attack once it has started. It can be used alone or in combination with some other medicines.
Trimetazidine should be taken regularly as advised by the doctor. You should take it with or without food and at a fixed time. Your doctor will decide how often you should take this medicine. This may change from time to time depending on how well it is working. You should take this medicine regularly to get the most benefit, even if you feel fine.
It helps in preventing future harm. If you stop taking it, your chest pain may come back. You can improve the health of your heart by making some lifestyle changes such as quitting smoking, cutting down on alcohol, eating well, taking regular exercise, and managing stress.
Some common side effects of this medicine include dizziness, headache, abdominal pain, diarrhea, indigestion, nausea, vomiting, rash, itching, hives, and weakness. Talk to your doctor if these effects bother you or do not go away.
This medicine may not be suitable for some people. You must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.
Uses of Trimetazidine
- Treatment of Angina (heart-related chest pain)
Benefits of Trimetazidine
Treatment of Angina (heart-related chest pain)
Angina is chest pain or discomfort that happens when there is not enough
oxygen-rich blood going to part of your heart. This can occur when the blood
vessels of the heart become narrow. Trimetazidine relaxes the blood vessels so
that blood can flow more easily and makes sure that your heart is getting a
good supply of oxygen. This makes it less likely that you will suffer chest
pain caused by angina. Trimetazidine can also help increase your ability to
exercise and lead your daily life more easily by reducing the frequency of
angina attacks. You should take it regularly and as long as it is prescribed
for it to work effectively.
Research shows that the frequency of angina attacks reduces significantly after 6 months of treatment with Trimetazidine.
Side effects of Trimetazidine
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Flavedon
- Dizziness
- Headache
- Nausea
- Vomiting
- Weakness
- Rash
- Abdominal pain
- Indigestion
- Itching
- Diarrhea
- Hives
How to use Trimetazidine
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trimetazidine may be taken with or without food, but it is better to take it at a fixed time.
How Trimetazidine works
Trimetazidine is an anti-anginal medication. It decreases the oxygen requirement of the heart by shifting its metabolism from fats to glucose. As a result, the heart works more efficiently.
Quick tips
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Trimetazidine prevents new attacks of angina but does not stop an acute attack.
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Does not affect heart rate, blood pressure at rest or during exercise.
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Improves HbA1c and blood sugar levels in diabetes patients.
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Avoid driving or using machinery if you feel dizzy after taking Trimetazidine.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Trimetazidine if I’m pregnant?
Information regarding the use of Trimetazidine during pregnancy is not available. Please consult your doctor.
BreastfeedingCONSULT YOUR DOCTOR
Can I take Trimetazidine if I’m breastfeeding?
Information regarding the use of Trimetazidine during breastfeeding is not available. Please consult your doctor.
AlcoholUNSAFE
Is drinking alcohol while taking Trimetazidine safe?
Trimetazidine may cause excessive drowsiness with alcohol.
DrivingUNSAFE
Can I drive after taking Trimetazidine?
Trimetazidine may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyCAUTION
Can I take Trimetazidine if I have/had kidney diseases?
Trimetazidine should be used with caution in patients with kidney disease. Dose adjustment of Trimetazidine may be needed. Please consult your doctor. Use of Trimetazidine is not recommended in patients with severe kidney disease.
LiverCONSULT YOUR DOCTOR
Can I take Trimetazidine if I have/had liver diseases?
There is limited information available on the use of Trimetazidine in patients with liver disease. Please consult your doctor.
Frequently Asked Questions
Q. Is Trimetazidine a beta blocker?
No, Trimetazidine is not a beta blocker. It is an anti-anginal medicine which is used in combination with other medicines to treat angina pectoris (chest pain caused by coronary disease). It protects the heart cells from getting affected by the reduced oxygen supply during an episode of angina.
Q. Who should not take Trimetazidine?
You should not take Trimetazidine if you are allergic to it or have severe kidney problems. Patients with Parkinson’s disease should also avoid taking Trimetazidine. Parkinson’s disease is a disease of the brain which affects movement and causes trembling, rigid posture, slow movements and a shuffling, unbalanced walk.
Q. Can Trimetazidine be used in elderly patients?
Trimetazidine should be used with caution in patients aged more than 75 years of age. Usually, a lower dose is prescribed in elderly patients to reduce the chances of adverse effects. It is important to continuously monitor such patients.
Q. Does taking Trimetazidine increases the risk of falling down frequently?
Though it is rare, falls may occur with use of Trimetazidine. This may be due to instability while walking or fall in blood pressure while standing up. The risk may be higher in elderly patients. Therefore, they need to be more careful and should be monitored.
Q. Does Trimetazidine cause drowsiness?
Yes, Trimetazidine may make you feel dizzy and drowsy. Therefore, you should avoid driving or using heavy machinery in case it causes these side effects.
Q. How should Trimetazidine be taken?
You should take Trimetazidine exactly as prescribed by your doctor. It is meant for oral use. So, take the tablets with sufficient amount of liquid, e.g. a glass of water. You can take this medicine with or without food.
Q. What are the possible side effects of Trimetazidine?
The common side effects of Trimetazidine include dizziness, headache, abdominal pain, diarrhea, indigestion, and hives, rash and itching. Its use may also make you feel sick and weak. The rare side effects may include fast or irregular heartbeats (also called palpitations), fall in blood pressure on standing which can further cause dizziness, lightheadedness or fainting, fall, and flushing.
References
Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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