Trientine Hydrochloride

Introduction To Trientine Hydrochloride

Trientine Hydrochloride is used to treat Wilson’s disease by removing excess copper from the body. It works by binding excess copper in body tissues, carrying it to the kidneys where it is finally removed via urine.

You should take it on an empty stomach, at least one hour before or two hours after meals. You may check body temperature every night for the first month of treatment. You should inform the doctor if you notice any symptoms like fever or skin eruptions. Your doctor may regularly check your blood iron levels. It may cause side effects like nausea, skin rash and anemia (low number of red blood cells).

Uses of Trientine Hydrochloride

  • Wilson's disease

Side effects of Trientine Hydrochloride

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Severe side effects of Jolltrin

  • Systemic lupus erythematosus
  • Iron deficiency
  • Dystonia (involuntary muscle contractions)
  • Muscle spasm
  • Myasthenia gravis

How to use Trientine Hydrochloride

Take this medicine in the dose and duration as advised by your doctor. Trientine Hydrochloride may be taken with or without food, but it is better to take it at a fixed time.

How Trientine Hydrochloride works

Trientine Hydrochloride is a copper chelating agent. It works by binding excess copper in body tissues, carrying it to the kidneys where it is finally removed via urine.

Quick tips

  • Trientine Hydrochloride treats Wilson’s disease by removing excess copper from the body.
  • Take it on an empty stomach, at least one hour before or two hours after meals.
  • It should be swallowed whole with water and should not be crushed or chewed. Take it at least one hour apart from any other drug.
  • Monitor your temperature every night for the first month of treatment. Inform your doctor if you notice symptoms such as fever or skin eruptions.
  • Your doctor may regularly monitor your blood iron level to check for iron deficiency.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Trientine Hydrochloride if I’m pregnant?

Trientine Hydrochloride may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Trientine Hydrochloride if I’m breastfeeding?

Information regarding the use of Trientine Hydrochloride during breastfeeding is not available. Please consult your doctor.

sdsDrivingCONSULT YOUR DOCTOR

Can I drive after taking Trientine Hydrochloride?

It is not known whether Trientine Hydrochloride alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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