Teneligliptin

Introduction To Teneligliptin

Teneligliptin is a medicine used to treat type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Teneligliptin is normally prescribed when diet and exercise alone or other medicines do not prove sufficient to control your blood sugar level. Your doctor may prescribe it alone or in combination with other diabetes medicines. It can be taken with or without food. The dose will depend on your condition and blood sugar levels. Use it strictly as advised by your doctor.

You should take it regularly at the same time each day to get the most benefit from it. Do not stop taking the medicine unless your doctor recommends it. This medicine helps you control your blood sugar levels and prevent serious complications in the future. It is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. Your lifestyle plays a big part in controlling diabetes.

The most common side effects of this medicine are hypoglycemia and constipation. It is important to recognize the symptoms of hypoglycemia (such as lightheadedness, sweating, dizziness, fainting, and dry mouth) and know how to deal with it. You can carry sugar or glucose candy and have them to control your symptoms if you experience any. Contact your doctor if the side effects if they do not go away or worry you.

Before taking this medicine, let your doctor know if you have ever had kidney disease, heart disease, or pancreas problems. Pregnant or breastfeeding women should also consult their doctor before taking it. Some other medicines you are taking may interfere with this medicine's working. So, make sure your doctor knows about all the other medicines you are using. Limit your alcohol intake while taking this medicine because it can increase your risk of developing low blood sugar levels. You may need regular tests such as kidney function and blood glucose levels to check that the medicine is working properly.

Uses of Teneligliptin

  • Treatment of Type 2 diabetes mellitus

Benefits of Teneligliptin

Treatment of Type 2 diabetes mellitus
Teneligliptin belongs to a group of medicines called DPP-4 inhibitors (or gliptins). It helps increase the amount of insulin your body produces after a meal and to stop your body from releasing too much glucose (sugar) into your blood. This way it lowers the blood glucose levels in your body. It is usually taken once a day and has relatively few common side effects.

Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, blindness, and loss of limbs. Proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed.

Side effects of Teneligliptin

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Efiglin

  • Dizziness
  • Headache
  • Diarrhea
  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Vomiting

How to use Teneligliptin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Teneligliptin may be taken with or without food, but it is better to take it at a fixed time.

How Teneligliptin works

Teneligliptin is an antidiabetic medication. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and postmeal sugar levels.

Quick tips

  • Teneligliptin should be taken at the same time every day since this helps you remember to take it.

  • Be careful while driving or operating machinery until you know how Teneligliptin affects you.

  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemia symptoms such as cold sweats, cool pale skin, tremor and anxiety.

  • Inform your doctor if you notice joint pains or develop symptoms such as stomach pain, nausea and/or vomiting.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Teneligliptin if I’m pregnant?

Teneligliptin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Teneligliptin if I’m breastfeeding?

Teneligliptin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Teneligliptin safe?

It is unsafe to consume alcohol with Teneligliptin.

sdsDrivingCAUTION

Can I drive after taking Teneligliptin?

Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.

sdsKidneySAFE IF PRESCRIBED

Can I take Teneligliptin if I have/had kidney diseases?

Teneligliptin is safe to use in patients with kidney disease. No dose adjustment of Teneligliptin is recommended.

sdsLiverSAFE IF PRESCRIBED

Can I take Teneligliptin if I have/had liver diseases?

Teneligliptin is safe to use in patients with liver disease. No dose adjustment of Teneligliptin is recommended. However, no clinical evidence is established for its use in patients with severe kidney impairment.

Frequently Asked Questions

Q. Does Teneligliptin cause weight gain?

No, Teneligliptin is not known to cause weight gain by itself. However, keeping a healthy weight is an important part of managing diabetes. Consult your doctor if you experience weight gain while taking Teneligliptin.

Q. Is Teneligliptin bad for your kidneys?

No, Teneligliptin is not bad for your kidneys if your kidney function is normal. However, it is important to inform your doctor if you have, or ever had, any kidney problems. If you have kidney problems, you may need dose modification.

Q. Do I still have to manage my diet and exercise while on Teneligliptin?

Yes, it is important to manage your diet and exercise while taking Teneligliptin. In addition to medicine, making healthy food choices and being physically active are also important to effectively manage blood sugar levels. You may consult a dietitian and follow a diet chart that suits you best. A well- balanced diet is one part of a healthy lifestyle for people with type 2 diabetes. Additionally, thirty minutes of exercise such as a brisk walk is recommended.

Q. Can my blood sugar levels go too low on Teneligliptin?

Yes, it is possible that your blood sugar levels may become very low (hypoglycemia). The chances are higher if you are on any other antidiabetic medicine or insulin along with Teneligliptin. Additionally, blood sugar levels can take a huge dip if you skip meals, exercise more than usual, or if you have taken an overdose of Teneligliptin. If you experience a sudden fall in your sugar levels, inform your doctor. The doctor may suggest dose modification to prevent your blood sugar levels from decreasing significantly (hypoglycemia). Follow your doctor’s advice and monitor your blood sugar levels regularly.

Q. How long do I need to take Teneligliptin?

Teneligliptin only helps to manage your blood sugar levels but does not cure your diabetes. Keep taking Teneligliptin as long as your doctor recommends it. You may have to take it lifelong. It is important to keep your blood sugar levels under control as any fluctuations in your blood sugar levels may cause serious problems. Therefore, do not stop taking it without talking to your doctor.

Q. What will happen if I accidentally take more than the prescribed dose of Teneligliptin?

If you have accidentally taken more than the prescribed dose of Teneligliptin, your blood sugar levels may become too low (hypoglycemia). This hypoglycemia may be mild or severe. Monitor your blood sugar levels more frequently for the next 24 hours. Mild episodes of hypoglycemia (with symptoms like anxiety, sweating, weakness, tremors, fast heartbeat) can usually be corrected with the help of sugary foods such as sugar or glucose candy, fruit juice and glucose/glucon-D. However, it is important to consult your doctor to decide the further course of treatment. More severe episodes of hypoglycemia may even lead to a seizure (fit) or unconsciousness. This can be life-threatening and immediate medical help may be required.

Q. What if I miss a dose of Teneligliptin?

If you miss a dose, take it as soon as you remember. If in case you do not remember until it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses of Teneligliptin at the same time.

Q. What is the most important information I should know about Teneligliptin?

Teneligliptin is safe to use if taken in the dose and duration prescribed by the doctor. However, in rare cases, some serious side effects can also be observed. In some people, Teneligliptin may cause inflammation of the pancreas (pancreatitis) which could be severe and can even lead to death. If you experience severe and persistent pain in your stomach area (abdomen), stop the medication and immediately contact your doctor. Teneligliptin can also cause heart failure. This means the heart is not able to pump blood well enough, therefore, inform your doctor if you have or ever had heart problems before you start taking Teneligliptin. In addition to that, problems related to kidneys should also be discussed with the doctor.

Q. Is Teneligliptin safe to be taken for a long term?

Yes, it is safe to take Teneligliptin for a long time. Its long-term use, which can continue for months, years or even lifelong, has not shown any harmful effects. Keep taking Teneligliptin as long as your doctor recommends it. Remember, Teneligliptin only helps to keep your blood sugar levels under control but does not cure your diabetes.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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