Suxamethonium
Introduction To Suxamethonium
Suxamethonium belongs to a group of medicines called muscle relaxants. It is used along with general anesthesia or sedatives to provide skeletal muscle relaxation during surgical procedures. It is also used to facilitate emergency airway management in patients in intensive care.
Suxamethonium is administered by a healthcare professional. You should not self- administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include stomach pressure, excessive salivation, muscle twitching, and postoperative muscle pain. Other common side effects include increased intraocular pressure, slow heart rate, increased heart rate, flushing of the skin, high blood pressure, low blood pressure, rash, and increased potassium level in blood. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, to make sure it is safe for you, you should let your doctor know if you have any other medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.
Uses of Suxamethonium
- Skeletal muscle relaxation during surgery
Benefits of Suxamethonium
Skeletal muscle relaxation during surgery
Suxamethonium is used to relax muscles during anesthesia and surgical procedures.
It works by blocking chemical messengers in the brain that are responsible for
rigidity, inflammation, or swelling. It effectively relieves muscle stiffness
or spasm, thereby improving muscle movement.
It is given as an injection by a doctor or nurse and should not be self-
administered. The dose and duration will be decided by the doctor depending on
the condition you are being treated for. This will help you to go about your
daily activities more easily and have a better, more active, quality of life.
Side effects of Suxamethonium
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Myorelex
- Stomach pressure
- Excessive salivation
- Muscle twitching
- Postoperative muscle pain
- Increased intraocular pressure
- Slow heart rate
- Increased heart rate
- Flushing of skin
- High blood pressure
- Hypotension (low blood pressure)
- Rash
- Increased potassium level in blood
How to use Suxamethonium
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Suxamethonium works
Suxamethonium relaxes the muscles by blocking the impulses from the nerves.
Quick tips
- Suxamethonium is given as an injection into vein under the supervision of a doctor.
- It makes you feel dizzy or drowsy. Do not drive until you know how Suxamethonium affects you.
- Your doctor will monitor your blood pressure regularly as the medicine may lead to high blood pressure.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Suxamethonium if I’m pregnant?
Suxamethonium may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingSAFE IF PRESCRIBED
Can I take Suxamethonium if I’m breastfeeding?
Suxamethonium is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
AlcoholCONSULT YOUR DOCTOR
Is drinking alcohol while taking Suxamethonium safe?
It is not known whether it is safe to consume alcohol with Suxamethonium. Please consult your doctor.
DrivingNOT RELEVANT
Can I drive after taking Suxamethonium?
Not relevant, as Suxamethonium is intended for use in hospitalised patients.
KidneyCAUTION
Can I take Suxamethonium if I have/had kidney diseases?
Suxamethonium should be used with caution in patients with kidney disease. Dose adjustment of Suxamethonium may be needed. Please consult your doctor.
LiverCAUTION
Can I take Suxamethonium if I have/had liver diseases?
Suxamethonium should be used with caution in patients with liver disease. Dose adjustment of Suxamethonium may be needed. Please consult your doctor.
Frequently Asked Questions
Q. Why does Suxamethonium cause bradycardia (abnormally slow heart beat)?
The initial metabolite of Suxamethonium produces a transient negative chronotropic effect through its stimulation of sinus node muscarinic receptors. Repeated dosing or infusions of Suxamethonium may lead to bradycardia that is appropriately treated with atropine
Q. Why does Suxamethonium cause fasciculation (twitching of muscles under the skin)?
Suxamethonium cause fasciculation by an action on some distal part of motor nerve fibres
Q. Is Suxamethonium still used?
Suxamethonium is still used during general anesthesia
Q. Is Suxamethonium reversible?
Suxamethonium is a short-acting muscle relaxant which exerts a depolarizing effect at the neuromuscular junction. This effect is not reversible pharmacologically
Q. Is Suxamethonium is contraindicated in burned patients?
Yes, Suxamethonium should not be used in burned patients
Q. Does Suxamethonium cross the placenta?
In normal therapeutic doses, Suxamethonium does not cross the placental barrier in sufficient amounts.
References
Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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