Rosuvastatin
Introduction To Rosuvastatin
Rosuvastatin belongs to a group of medicines called statins. It is used to lower cholesterol and reduce the risk of heart disease. Cholesterol is a fatty substance that builds up in your blood vessels and causes narrowing, which may lead to a heart attack or stroke.
Rosuvastatin is a widely prescribed medicine and is regarded as safe for long- term use. It can be taken with a meal or on an empty stomach. You can take it at any time of the day but try to take it at the same time each day. Most people with high cholesterol do not feel ill, but stopping your medicine may increase your cholesterol levels, making your condition worse and increasing your risk of heart disease and stroke.
It is important to have your cholesterol levels checked regularly. This medicine is only one part of the treatment program which should also include a healthy diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat.
Common side effects of this medicine include muscle pain, weakness, nausea, headache, and stomach pain. These are usually mild and disappear after a short time. Consult your doctor if they persist or if you notice any yellowing of your eyes or get repeated or unexplained muscle pains.
This medicine should not be used in conditions such as liver disease. Also, pregnant women and breastfeeding mothers should not take this medicine as it may harm the developing baby. Diabetic patients should monitor their blood sugar levels while taking this medicine, as it may lead to an increase in blood sugar levels.
Uses of Rosuvastatin
- Treatment of High cholesterol
- Prevention of heart attack and stroke
Benefits of Rosuvastatin
Treatment of High cholesterol
Rosuvastatin belongs to a group of medicines called statins. It works by
reducing the amount of “bad” cholesterol (LDL) and raising the amount of
“good” cholesterol (HDL) in your blood. Lowering the amount of cholesterol
reduces the chances of heart diseases and helps you remain healthier for
longer.
Take it regularly and make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine. Keep taking it even if you feel well.
Prevention of heart attack and stroke
High levels of cholesterol can cause your blood vessels to narrow
(atherosclerosis) and put you at risk of having a stroke or heart disease.
Lowering the amount of this fat reduces the chances of this happening and
helps you remain healthier for longer. Keep taking this medicine even if you
feel well.
Side effects of Rosuvastatin
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Rozavel
- Muscle pain
- Weakness
- Headache
- Abdominal pain
- Dizziness
- Joint pain
- Nausea
How to use Rosuvastatin
Take this medicine in the dose and duration as advised by your doctor. Rosuvastatin may be taken with or without food, but it is better to take it at a fixed time.
How Rosuvastatin works
Rosuvastatin is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).
Quick tips
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Rosuvastatin treats high cholesterol by lowering "bad" cholesterol (LDL) and triglycerides (fats). It should be taken in addition to regular exercise and low-fat diet.
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In general, Rosuvastatin is safe. It may cause diarrhea, gas or an upset stomach. If any of these happen to you, take it with food.
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Inform your doctor if you experience fatigue, muscle weakness or muscle pain.
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Your doctor may check your liver function before starting the treatment and regularly thereafter. Inform your doctor if you notice signs of liver problems such as stomach pains, unusually dark urine or yellowing of skin or eyes.
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Inform your doctor if you have kidney disease, liver disease or diabetes before starting treatment with this medicine. If you are diabetic, monitor your blood sugar level regularly as Rosuvastatin may cause an increase in your blood sugar level.
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Do not take Rosuvastatin if you are pregnant, planning a pregnancy or breastfeeding.
Safety Advice
PregnancyUNSAFE
Can I take Rosuvastatin if I’m pregnant?
Rosuvastatin is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
BreastfeedingUNSAFE
Can I take Rosuvastatin if I’m breastfeeding?
Rosuvastatin is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
AlcoholCAUTION
Is drinking alcohol while taking Rosuvastatin safe?
Caution is advised when consuming alcohol with Rosuvastatin. Please consult your doctor.
DrivingSAFE
Can I drive after taking Rosuvastatin?
Rosuvastatin does not usually affect your ability to drive.
KidneyCAUTION
Can I take Rosuvastatin if I have/had kidney diseases?
Rosuvastatin should be used with caution in patients with kidney disease. Dose adjustment of Rosuvastatin may be needed. Please consult your doctor. Use of Rosuvastatin is not recommended in patients with severe kidney disease.
LiverCAUTION
Can I take Rosuvastatin if I have/had liver diseases?
Rosuvastatin should be used with caution in patients with liver disease. Dose adjustment of Rosuvastatin may be needed. Please consult your doctor. Use of Rosuvastatin is not recommended in patients with severe liver disease and active liver disease.
Frequently Asked Questions
Q. For how long should I take Rosuvastatin?
You may need to take Rosuvastatin for life or for as long as directed by your doctor. The cholesterol levels will be maintained only till you are taking Rosuvastatin. Stopping Rosuvastatin without starting a different treatment may increase your cholesterol levels again. This medicine has only a few side effects and is usually considered safe if taken as directed by the doctor.
Q. Does Rosuvastatin cause weight gain?
No, there is no evidence of Rosuvastatin causing weight gain. If you are taking Rosuvastatin and gaining weight, consult your doctor. The doctor may get some investigations done to know the reason for the weight gain.
Q. Does Rosuvastatin make you tired?
Yes, Rosuvastatin can make you feel tired. This is because it reduces the energy supply to the muscles in the body. However, the exact reason behind the phenomenon is unknown and needs more research. Tiredness usually occurs after exertion. Generalized fatigue is more often in people with heart disease or those suffering from liver illness. Rosuvastatin also causes muscle damage which further worsens the tiredness. Therefore, you must consult your doctor if you feel tired while taking Rosuvastatin.
Q. Should Rosuvastatin be taken at night?
Rosuvastatin should be taken once a day. It can be taken in the morning or at night or any time of the day, with or without food. Try taking this medicine at the same time every day. Doing this will help you remember to take it daily.
Q. What foods should be avoided when taking Rosuvastatin?
Rosuvastatin is used to decrease your blood cholesterol levels. Therefore, to seek the best results of this medicine, you should avoid foods that are high in calories like fried food and junk food. It is recommended to eat a low-fat and low-cholesterol diet. Be sure to follow all the exercise and dietary recommendations made by your doctor or dietician.
Q. How do I know whether Rosuvastatin is beneficial for me or not?
All medicines have side effects, but the benefits of Rosuvastatin in reducing cholesterol levels and the risk of heart attack and stroke are proven by a large number of studies. However, if you do have any concerns, then discuss it with your doctor. Your doctor will consider and explain to you the benefits of taking Rosuvastatin versus the risks of not taking it at all.
Q. Can Rosuvastatin cause memory loss?
Rosuvastatin may cause memory loss in very rare cases. This is generally non- serious and may occur within 1 day of taking this medicine or may take years to appear. These symptoms may disappear within about 3 weeks of discontinuing Rosuvastatin. However, you should consult your doctor if you experience this side effect as it could be due to some other reason.
Q. Can Rosuvastatin cause muscle problems or muscle injury?
Yes, taking Rosuvastatin can cause muscle problems or muscle injury. This is because of the reduced oxygen supply to the muscle cells which leads to fatigue, muscle pain, tenderness or muscle weakness. The soreness may be significant enough to interfere with your daily activities. Do not take it lightly and consult your doctor to know about ways to prevent this and to avoid making it worse.
Q. Is it true that Rosuvastatin can cause diabetes?
If you are at high risk of developing type 2 diabetes, taking Rosuvastatin may slightly increase this risk. This is because Rosuvastatin has the potential to cause a slight increase in your blood sugar levels. If you already have type 2 diabetes, your doctor may advise you to keep monitoring your blood sugar levels closely for the first few months. Tell your doctor if you find it harder to control your blood sugar.
References
Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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