Pyrimethamine + Sulphadoxine

Pyrimethamine + Sulphadoxine is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body.

Pyrimethamine + Sulphadoxine is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.

Some common side effects of this medicine are headaches, diarrhea, nausea, vomiting, weakness, indigestion, etc. You may also feel dizzy, thus it is advised not to drive or operate machinery. To overcome dizziness you should drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately.

Before taking this medicine, you should tell your doctor if you are taking any medication for any health conditions. Pregnant or breastfeeding women should also consult with their doctor before taking it. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine.

• Treatment of Malaria

Treatment of Malaria
Malaria is a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. Pyrimethamine + Sulphadoxine is an antimalarial medicine and is used to treat malaria. It kills the infection- causing parasite and stops the further spread of the infection in the body. Do not use this medicine for treating any other condition without consulting your doctor.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Malarprim

• Nausea
• Vomiting
• Diarrhea
• Fatigue
• Feeling of fullness
• Dizziness
• Headache
• Mouth sore
• Skin rash

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Pyrimethamine + Sulphadoxine is to be taken with food.

Pyrimethamine + Sulphadoxine is a combination of two medicines: Pyrimethamine and Sulphadoxine which treat malaria. Pyrimethamine is an antiparasitic medicine which works by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. Sulphadoxine is an antibiotic which stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.

• Pyrimethamine + Sulphadoxine must be taken with food at the same time every day.
• Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
• It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.
• It may cause dizziness. Do not drive or do anything that requires mental focus until you know how medicine affects you.
• Avoid consuming alcohol while taking medication as it may cause increased side effects.
• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Pyrimethamine+Sulphadoxine. Basel, Switzerland: F. Hoffmann-La Roche Ltd. [Accessed 10 Apr. 2019] (online) Available from:

Pyrimethamine. Research Triangle Park, North Carolina: DSM Pharmaceuticals; 2003. [Accessed 10 Apr. 2019] (online) Available from:

ScienceDirect. Sulphadoxine. [Accessed 10 Apr. 2019] (online) Available from: