Palonosetron

Palonosetron is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy or radiotherapy.

Palonosetron will not relieve other side effects associated with cancer treatments. It is given under the supervision of a doctor and may be used alone or with other medications. Your doctor will give you the appropriate dose of the medicine depending on what you are taking it for. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of the injections.

The most common side effects of taking this medicine include injection site pain, headache, and constipation. Dizziness and sleepiness may also occur, so do not drive or do anything that requires mental focus until you know how this medicine affects you. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, consult your doctor who may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicine you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your healthcare team.

• Nausea
• Vomiting

Nausea
Palonosetron blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting associated with cancer treatment such as chemotherapy or radiation therapy in adults as well as children. This medicine helps you recover more comfortably from these treatments. Palonosetron is also effective at preventing nausea and vomiting after an operation (in adults only). Palonosetron is given as an injection by a doctor, in the dose that is best for you, depending on the condition you are being treated for. Do not self-administer this medicine to avoid any undesirable side effects.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Emecad

• Injection site pain
• Constipation
• Headache
• Diarrhea
• Dizziness

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Palonosetron is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

• You have been prescribed Palonosetron for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
• Palonosetron is given as an injection under the supervision of a doctor.
• If you vomit within one hour of taking a dose, take another dose.
• Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.

Palonosetron. Mulhuddart Dublin: Helsinn Birex Pharmaceuticals Ltd.; 2005 [revised 26 Apr. 2018]. [Accessed 28 Mar. 2019] (online) Available from:

Palonosetron. Bloomington, MN: MGI PHARMA, INC; 2006. [Accessed 28 Mar. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from: