Ondansetron + Ranitidine

Ondansetron + Ranitidine is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux), acidity, nausea and vomiting. It relieves the symptoms of acidity such as indigestion, stomach pain, or irritation. It also decreases the acid production in the stomach to relieve heartburn.

Ondansetron + Ranitidine is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are diarrhea, constipation, headache, fatigue, muscle pain, dryness in mouth, and flushing of skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before you start taking this medicine it is important to inform your doctor if you are suffering from liver disease. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

• Gastroesophageal reflux disease (Acid reflux)
• Nausea
• Acidity

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Ondansetron + Ranitidine reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective. Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Nausea
Ondansetron + Ranitidine blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always follow your doctor’s instructions carefully to get the most benefit.

Acidity
Ondansetron + Ranitidine relieves excessive acidity in your stomach which prevents heartburn, irritation, stomach pain, and indigestion. Usually, it is used along with other medicines for management of your condition. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ondarom-R

• Diarrhea
• Constipation
• Headache
• Drowsiness
• Fatigue
• Muscle pain
• Dryness in mouth
• Flushing of skin

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Ondansetron + Ranitidine is a combination of two medicines: Ondansetron and ranitidine which prevent nausea and vomiting. Ondansetron is an antiemetic (anti-nausea medicine). It inhibits the action of serotonin, a chemical messenger that can trigger nausea and vomiting. Ranitidine is an H2 blocker (antacid). It works by reducing the amount of acid in the stomach which helps in relief of acid- related indigestion and heartburn.

• Ondansetron + Ranitidine is administered to give relief from nausea, vomiting as well as acidity, heartburn and other discomfort associated with acid reflux.

• Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.

• Incorporate the folowing lifestyle changes in order to prevent acidity:

  1. Make sure you eat regular meals and drink plenty of water.
  2. Avoid spicy and fatty fried food.
  3. Lose weight if you are obese.
  4. If you are a smoker, consider giving up.
  5. Don't drink too much alcohol.
  6. Do not go to bed immediately after taking a meal. Sit in a relaxed position for sometimes for better digestion.

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ScienceDirect. Ranitidine. [Accessed 28 Mar. 2019] (online) Available from: