Ondansetron + Ranitidine

Introduction To Ondansetron + Ranitidine

Ondansetron + Ranitidine is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux), acidity, nausea and vomiting. It relieves the symptoms of acidity such as indigestion, stomach pain, or irritation. It also decreases the acid production in the stomach to relieve heartburn.

Ondansetron + Ranitidine is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are diarrhea, constipation, headache, fatigue, muscle pain, dryness in mouth, and flushing of skin. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before you start taking this medicine it is important to inform your doctor if you are suffering from liver disease. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Uses of Ondansetron + Ranitidine

  • Gastroesophageal reflux disease (Acid reflux)
  • Nausea
  • Acidity

Benefits of Ondansetron + Ranitidine

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Ondansetron + Ranitidine reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective. Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Nausea
Ondansetron + Ranitidine blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always follow your doctor’s instructions carefully to get the most benefit.

Acidity
Ondansetron + Ranitidine relieves excessive acidity in your stomach which prevents heartburn, irritation, stomach pain, and indigestion. Usually, it is used along with other medicines for management of your condition. Take a fiber-rich diet, avoid oily or spicy food and drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Ondansetron + Ranitidine

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ondarom-R

  • Diarrhea
  • Constipation
  • Headache
  • Drowsiness
  • Fatigue
  • Muscle pain
  • Dryness in mouth
  • Flushing of skin

How to use Ondansetron + Ranitidine

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Ondansetron + Ranitidine works

Ondansetron + Ranitidine is a combination of two medicines: Ondansetron and ranitidine which prevent nausea and vomiting. Ondansetron is an antiemetic (anti-nausea medicine). It inhibits the action of serotonin, a chemical messenger that can trigger nausea and vomiting. Ranitidine is an H2 blocker (antacid). It works by reducing the amount of acid in the stomach which helps in relief of acid- related indigestion and heartburn.

Quick tips

  • Ondansetron + Ranitidine is administered to give relief from nausea, vomiting as well as acidity, heartburn and other discomfort associated with acid reflux.

  • Avoid taking soft drinks, citrus fruits like orange and lemon, which can irritate the stomach and increase acid secretion.

  • Incorporate the folowing lifestyle changes in order to prevent acidity:

    1. Make sure you eat regular meals and drink plenty of water.
    2. Avoid spicy and fatty fried food.
    3. Lose weight if you are obese.
    4. If you are a smoker, consider giving up.
    5. Don't drink too much alcohol.
    6. Do not go to bed immediately after taking a meal. Sit in a relaxed position for sometimes for better digestion.

Safety Advice

sdsPregnancySAFE IF PRESCRIBED

Can I take Ondansetron + Ranitidine if I’m pregnant?

Ondansetron + Ranitidine is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

sdsBreastfeedingSAFE IF PRESCRIBED

Can I take Ondansetron + Ranitidine if I’m breastfeeding?

Ondansetron + Ranitidine is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Ondansetron + Ranitidine safe?

It is unsafe to consume alcohol with Ondansetron + Ranitidine.

sdsDrivingSAFE

Can I drive after taking Ondansetron + Ranitidine?

Ondansetron + Ranitidine does not usually affect your ability to drive.

sdsKidneyCAUTION

Can I take Ondansetron + Ranitidine if I have/had kidney diseases?

Ondansetron + Ranitidine should be used with caution in patients with kidney disease. Dose adjustment of Ondansetron + Ranitidine may be needed. Please consult your doctor.

sdsLiverCAUTION

Can I take Ondansetron + Ranitidine if I have/had liver diseases?

Ondansetron + Ranitidine should be used with caution in patients with liver disease. Dose adjustment of Ondansetron + Ranitidine may be needed. Please consult your doctor.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

Disclaimer: The contents of this material are solely intended for informational purposes and do not serve as a substitute for professional medical advice, diagnosis, or treatment. MediClap does not offer advice, endorse any specific prescription drug, pharmacy, or other information on the site. Furthermore, MediClap does not provide any warranty for the information presented. It is recommended that you seek medical advice prior to commencing, altering, or terminating any medical treatment.
MediClap strives to make its website accessible to all users, including those with disabilities. Should you encounter any difficulty accessing this website, kindly send an email to hello@mediclap.com to enable us to provide the necessary services through alternative means.
MediClap is not affiliated with nor sponsored by any of the third-party brands mentioned. All trademarks, brands, logos, and copyrights mentioned remain the sole property of their respective owners.