Nebivolol

Introduction To Nebivolol

Nebivolol belongs to a group of medicines called beta-blockers. It is used to treat high blood pressure (hypertension). It also helps to prevent future heart attacks and stroke and to prevent migraines.

Nebivolol is also used to relieve the symptoms caused by an overactive thyroid gland. It may be prescribed alone or together with other medications. The dose and frequency depend on what you are taking it for and the severity of your condition. It may be taken empty stomach or with a meal, but take it regularly at the same time each day to get the most benefit. It may take several weeks before you get the full benefit of this medicine and you may need to take it for the rest of your life. However, it is important to continue taking it even if you feel well. Most people with high blood pressure do not feel ill and if you stop taking it, your condition may worsen. Lifestyle changes like low-fat diet, exercise, and no smoking help to enhance the working of this medicine.

The main side effects of this medicine are fatigue, headache, slow heart rate, feeling dizzy, and nausea. These are usually mild and short-lived. It may also cause shortness of breath or low blood pressure in some people. To reduce the risk of side effects your doctor will probably start the medicine at a low dose and gradually increase it. Consult your doctor if the side effects bother you or do not go away.

Before taking it, let your doctor know if you have any liver problems. It may also not be suitable for people who have a slow heart rate, severe circulation problems, severe heart failure, or low blood pressure. Pregnant or breastfeeding mothers should also consult their doctor before taking it. You must talk to your doctor to find out whether this medicine is suitable for you to use. You should have your blood pressure checked regularly to make sure that this medicine is working properly. Avoid drinking alcohol as it may increase certain side effects.

Uses of Nebivolol

  • Treatment of Hypertension (high blood pressure)
  • Prevention of Heart attack
  • Prevention of Stroke
  • Prevention of Migraine

Benefits of Nebivolol

Treatment of Hypertension (high blood pressure)
Nebivolol belongs to a group of medicine called long-acting beta-blocker. It works by blocking the effects of some chemicals on your heart and blood vessels. It slows down your heart rate and helps the heart beat with less force. This lowers your blood pressure and helps in reducing your risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

Prevention of Heart attack
Nebivolol helps lower your blood pressure and make it easier for your heart to pump blood around your body. This reduces the chances of you having a heart attack. It can also reduce the risk of dying if it is given immediately after a heart attack. This medicine needs to be taken regularly to be effective, so keep taking it even if you feel well. Do not stop without talking to your doctor.

Prevention of Stroke
Nebivolol reduces the risk of future strokes. It helps lower your blood pressure and makes it easier for your heart to pump blood around your body. This reduces the chances of you having a stroke. Take it as advised by the doctor to get the maximum benefit.

Prevention of Migraine
Nebivolol helps improve the flow of blood in your brain and prevents the abnormal activity of muscles that trigger migraines. It is a very effective medicine for preventing migraine attacks, however, it does not treat an attack that has already started. By preventing and reducing the frequency of migraine attacks, the medicine can help you carry out your daily activities and improve your quality of life.

Side effects of Nebivolol

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nebawol

  • Nausea
  • Headache
  • Slow heart rate
  • Fatigue
  • Constipation
  • Diarrhea
  • Dizziness
  • Cold extremities

How to use Nebivolol

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nebivolol may be taken with or without food, but it is better to take it at a fixed time.

How Nebivolol works

Nebivolol is a beta blocker that works specifically on the heart. It works by slowing down the heart rate and makes the heart more efficient at pumping blood around the body.

Quick tips

  • Nebivolol lowers your blood pressure and makes it easier for your heart to pump blood around your body.

  • Lowering high blood pressure helps prevent stroke and heart attack.

  • It may cause dizziness. If this happens to you, get up slowly when rising from a sitting or lying position.

  • It can hide symptoms of low blood sugar if you are diabetic. Monitor your blood sugar levels regularly.

  • Do not stop taking Nebivolol suddenly as it can cause your blood pressure to rise suddenly, thereby increasing the risk of heart attack and stroke.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Nebivolol if I’m pregnant?

Nebivolol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Nebivolol if I’m breastfeeding?

Nebivolol is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

sdsAlcoholCAUTION

Is drinking alcohol while taking Nebivolol safe?

Caution is advised when consuming alcohol with Nebivolol. Please consult your doctor.

sdsDrivingUNSAFE

Can I drive after taking Nebivolol?

Nebivolol may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

sdsKidneyCAUTION

Can I take Nebivolol if I have/had kidney diseases?

Nebivolol should be used with caution in patients with severe kidney disease. Dose adjustment of Nebivolol may be needed. Please consult your doctor.

sdsLiverCAUTION

Can I take Nebivolol if I have/had liver diseases?

Nebivolol should be used with caution in patients with liver disease. Dose adjustment of Nebivolol may be needed. Please consult your doctor. Use of Nebivolol is not recommended in patients with severe liver disease.

Frequently Asked Questions

Q. How long does Nebivolol take to start working?

After 1 to 2 weeks of starting Nebivolol your blood pressure may decrease. However, it may take 4 weeks to see full benefits.

Q. Now that my blood pressure has become normal, can I stop taking Nebivolol?

No, you should not stop taking Nebivolol even if you start feeling better. Nebivolol controls high blood pressure but does not cure it. If you stop Nebivolol suddenly, you may increase your chances of having angina, heart attack, or irregular heart-beat. Talk to your doctor who may advise you to decrease the dose gradually over 1 to 2 weeks.

Q. What can happen if I take more than the recommended doses of Nebivolol?

Taking more than the recommended doses of Nebivolol may cause very slow heart-beat, low blood pressure with possible fainting, difficulty in breathing or shortness of breath, and acute heart failure. In case you take excess of Nebivolol, contact your doctor immediately.

Q. Can Nebivolol be taken if I am taking ibuprofen?

You have to be careful while taking both ibuprofen and Nebivolol and keep monitoring your blood pressure on a regular basis. The reason being, ibuprofen may interfere with the working of Nebivolol and your blood pressure may increase. Similarly, discontinuing ibuprofen may decrease your blood pressure. This is usually seen in cases where ibuprofen is used for a longer time.

Q. I am a diabetic. Can taking Nebivolol affect my blood sugar levels?

No, Nebivolol does not have any effect on blood sugar levels. However, keep tracking your blood sugar levels because use of Nebivolol may mask the symptoms of low blood sugar levels, like fast heartbeat and palpitations.

Q. Can Nebivolol be given to old age patients?

Yes, Nebivolol can be given to patients who are 65 or above, but strictly as per the doctor’s advice. In this patient group, the doctor would recommend to start with the lowest dose and gradually reach the desired dosage. In patients who are 75 years or older, close monitoring of blood pressure is required.

Q. Does Nebivolol cause weight gain?

No, Nebivolol has not been reported to cause weight gain. Talk to your doctor if you experience weight gain while taking Nebivolol as it could be due to some other underlying condition.

Q. Does Nebivolol cross the blood-brain barrier?

Yes, Nebivolol crosses the blood-brain barrier due to its lipophilic nature. Its lipophilic nature makes it capable of combining with lipids and fats. So, it is effective in the treatment of migraine and essential tremors. This could also cause higher chances of central nervous system effects such as lethargy, confusion, and depression.

Q. What is the risk associated with Nebivolol if I take it during pregnancy?

Nebivolol should not be used during pregnancy since it decreases blood supply to the unborn baby which can result in death of the child in the womb. Decreased blood supply can slow down or retard the growth of the baby and may even lead to abortion or early labor. Inform your doctor that you are using Nebivolol if you have become pregnant, so that the doctor can change your medication.

Q. Does Nebivolol cause fatigue?

Nebivolol may cause fatigue (tiredness) and dizziness. Be very cautious while driving or using any machines or tools. Talk to your doctor if you have these problems while taking Nebivolol.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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