Mosapride

Mosapride is a prescription medicine used in the treatment of gastroesophageal reflux disease. It increases the release of certain chemical that improves the movement of food inside the intestine and helps to increase gastric emptying of both liquid and solid.

Mosapride is taken with or without food in a dose and duration as advised by the doctor. The dose you're given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are abdominal pain, headache, insomnia (difficulty sleeping), nausea, and vomiting. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should avoid this medicine if you are suffering from bleeding ulcers of the stomach. Consult with your doctor if are pregnant or breastfeeding.

• Gastroesophageal reflux disease (Acid reflux)

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above your stomach relaxes too much and allows stomach contents to come back up into your esophagus and mouth. Mosapride reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Mozatone

• Abdominal pain
• Dizziness
• Headache
• Insomnia (difficulty in sleeping)
• Nausea
• Vomiting

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mosapride may be taken with or without food, but it is better to take it at a fixed time.

Mosapride indirectly stimulates the release of acetylcholine, a chemical messenger that can increase the motility of the intestine.

• Take it at the same time every day, either with or without food.
• Do not skip any dose and finish the complete course as suggested by the doctor.
• Use caution while driving or doing anything that requires concentration as Mosapride can cause dizziness and sleepiness.
• Avoid alcohol and drink plenty of fluids to stay hydrated while taking this medicine.

Halpert A, Drossma D. 5-HTmodulators and other antidiarrheal agents and cathartics. In: Wolfe MM, Lowe RC, editors. Pocket Guide to Gastrointestinal Drugs. New Delhi: Wiley Blackwell; 2014. pp. 68-69.

ScienceDirect. Mosapride. [Accessed 28 Mar. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from: