Metronidazole + Ofloxacin

Introduction To Metronidazole + Ofloxacin

Metronidazole + Ofloxacin is an antibiotic medicine that is effective against a wide range of bacterial and parasitic infections. In children, it is used to treat infections of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract.

Give Metronidazole + Ofloxacin to your child orally, preferably at a fixed time, either before or after food. In case your child develops a stomach upset, prefer giving it with food. The usually prescribed frequency is twice a day, once in the morning and once in the evening. If your child vomits within 30 minutes of intake, repeat the same dose but never double up the dose if it is time for the next dose. The dose and duration depend upon the type and severity of the infection, your child's age, and body weight, so stick to the dose, time, and way prescribed by the doctor.

Some children may develop minor and temporary side effects after taking this medicine. These include nausea, vomiting, metallic taste, headache, loss of appetite, abdominal cramps, and mild skin rash. These side effects usually go away once your child's body adapts to the medicine. However, in case they persist for long or start bothering your child, you must consult your child's doctor without any delay.

Your child's doctor must be aware if your child has ever had any previous episode of allergy, heart problem, liver impairment, and kidney malfunction. This will guide the doctor in planning your child's overall treatment.

Uses of Metronidazole + Ofloxacin

  • Treatment of Bacterial & parasitic infections
  • Treatment of Diarrhea
  • Treatment of Dysentery

Benefits of Metronidazole + Ofloxacin

Treatment of Bacterial & parasitic infections
Metronidazole + Ofloxacin is an antibiotic medicine given to children for the treatment of a wide range of bacterial and parasitic infections. These infections may include tooth abscess, gum infection, pneumonia, diarrhea, dysentery, burning sensation while passing urine, and genital tract infection. Metronidazole + Ofloxacin inhibits the growth of infection-causing organisms by stopping them from multiplying. It is most likely that your child’s infection will start showing improvement within 3 to 5 days of the regular dosing. Make sure to complete the full course of treatment even if your child feels better. Stopping the medicine abruptly by yourself may worsen your child’s condition or cause infection recurrence.

Treatment of Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Metronidazole + Ofloxacin helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Treatment of Dysentery
Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Metronidazole + Ofloxacin helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Metronidazole + Ofloxacin

Metronidazole + Ofloxacin does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Spanflox M

  • Vomiting
  • Nausea
  • Weight loss
  • Abdominal pain
  • Diarrhea
  • Loss of appetite
  • Headache
  • Dizziness
  • Insomnia (difficulty in sleeping)
  • Metallic taste
  • Urine discoloration

How to use Metronidazole + Ofloxacin

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Metronidazole + Ofloxacin may be taken with or without food, but it is better to take it at a fixed time.

How Metronidazole + Ofloxacin works

Metronidazole + Ofloxacin is an antibiotic, having ofloxacin and metronidazole as its active ingredients. Both these medicines damage the DNA of the infection-causing bacteria, thus killing it by stopping its growth. This prevents the infection from spreading without making the bacteria resistant to further treatment.

Quick tips

  • If your child develops diarrhea as a side effect, encourage them to drink plenty of water.
  • Metronidazole + Ofloxacin may cause an altered taste. Eating citrus fruit or sipping plenty of water or fruit juice may help.
  • Do not give any calcium, magnesium, iron, vitamin, or antacid to your child within 2 hours of taking Metronidazole + Ofloxacin as these can affect the absorption of the medicine.
  • Conditions like common cold and flu are caused by viruses. Never use this medicine for such conditions.
  • Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
  • Discontinue Metronidazole + Ofloxacin and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or has difficulty in breathing.
  • Never save the medicine for future illnesses since its effectiveness in future infections cannot be guaranteed.

Safety Advice

sdsKidneyCAUTION

Can I take Metronidazole + Ofloxacin if I have/had kidney diseases?

Metronidazole + Ofloxacin should be used with caution in patients with kidney disease. Dose adjustment of Metronidazole + Ofloxacin may be needed. Please consult your doctor.

sdsLiverCAUTION

Can I take Metronidazole + Ofloxacin if I have/had liver diseases?

Metronidazole + Ofloxacin should be used with caution in patients with liver disease. Dose adjustment of Metronidazole + Ofloxacin may be needed. Please consult your doctor.

Frequently Asked Questions

Q. What if I give excess Metronidazole + Ofloxacin by mistake?

Although an extra dose of Metronidazole + Ofloxacin will not have any side effects, you must always be vigilant. If you think you have given too much Metronidazole + Ofloxacin to your child, immediately speak to a doctor. Overdose increases the risk of unwanted side effects such as seizures, tremors, severe headache, sudden weakness, blood cell abnormalities, and rapid and irregular heartbeat. Rush to your child’s doctor on an immediate basis if you notice any of these symptoms.

Q. What should I do if my child shows no improvement even after taking Metronidazole + Ofloxacin for the prescribed duration?

Ineffective treatment with Metronidazole + Ofloxacin could mean that the medicine is not able to act against the infection-causing bacteria. In such a case, visit your child’s doctor who may prescribe some other antibiotic, having more specific action toward the infection-causing bacteria.

Q. Can other medicines be given at the same time as Metronidazole + Ofloxacin?

Metronidazole + Ofloxacin can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Metronidazole + Ofloxacin. Also, check with your child’s doctor before giving any medicine to your child.

Q. Can I get my child vaccinated while on treatment with Metronidazole + Ofloxacin?

Antibiotics usually do not interfere with the ingredients in vaccines or cause a bad reaction in a child who has just been vaccinated. However, children taking antibiotics should not get vaccinated until they recover from the illness. As soon as your child feels better, the vaccine can be given.

Q. What should I tell the doctor before giving Metronidazole + Ofloxacin to my child?

Inform the doctor if your child is suffering from heart disease, genetic disorders involving blood vessels, seizures, psychiatric disorders, diabetes, photoallergy (allergy from sunlight), neuromuscular disorders, or rheumatoid arthritis. This is because there is a possibility that Metronidazole + Ofloxacin may aggravate these conditions and result in complications.

Q. My child has been passing red-brown urine ever since he started taking Metronidazole + Ofloxacin. Is it normal?

Yes, it is normal. Metronidazole + Ofloxacin contains an active ingredient called metronidazole which can cause red-brown urine. It is a harmless side effect. It will subside once the medicine is stopped after the completion of the treatment.

Q. My child is having a common cold. Is it safe to give Metronidazole + Ofloxacin along with cough & cold medicines?

No, do not give Metronidazole + Ofloxacin with cough and cold medicines as it can interfere with their working.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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