Metronidazole + Ofloxacin

Metronidazole + Ofloxacin is an antibiotic medicine that is effective against a wide range of bacterial and parasitic infections. In children, it is used to treat infections of the teeth, lungs, gastrointestinal tract, urinary tract, and genital tract.

Give Metronidazole + Ofloxacin to your child orally, preferably at a fixed time, either before or after food. In case your child develops a stomach upset, prefer giving it with food. The usually prescribed frequency is twice a day, once in the morning and once in the evening. If your child vomits within 30 minutes of intake, repeat the same dose but never double up the dose if it is time for the next dose. The dose and duration depend upon the type and severity of the infection, your child's age, and body weight, so stick to the dose, time, and way prescribed by the doctor.

Some children may develop minor and temporary side effects after taking this medicine. These include nausea, vomiting, metallic taste, headache, loss of appetite, abdominal cramps, and mild skin rash. These side effects usually go away once your child's body adapts to the medicine. However, in case they persist for long or start bothering your child, you must consult your child's doctor without any delay.

Your child's doctor must be aware if your child has ever had any previous episode of allergy, heart problem, liver impairment, and kidney malfunction. This will guide the doctor in planning your child's overall treatment.

• Treatment of Bacterial & parasitic infections
• Treatment of Diarrhea
• Treatment of Dysentery

Treatment of Bacterial & parasitic infections
Metronidazole + Ofloxacin is an antibiotic medicine given to children for the treatment of a wide range of bacterial and parasitic infections. These infections may include tooth abscess, gum infection, pneumonia, diarrhea, dysentery, burning sensation while passing urine, and genital tract infection. Metronidazole + Ofloxacin inhibits the growth of infection-causing organisms by stopping them from multiplying. It is most likely that your child’s infection will start showing improvement within 3 to 5 days of the regular dosing. Make sure to complete the full course of treatment even if your child feels better. Stopping the medicine abruptly by yourself may worsen your child’s condition or cause infection recurrence.

Treatment of Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Metronidazole + Ofloxacin helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Treatment of Dysentery
Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Metronidazole + Ofloxacin helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Metronidazole + Ofloxacin does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-

Common side effects of Spanflox M

• Vomiting
• Nausea
• Weight loss
• Abdominal pain
• Diarrhea
• Loss of appetite
• Headache
• Dizziness
• Insomnia (difficulty in sleeping)
• Metallic taste
• Urine discoloration

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Metronidazole + Ofloxacin may be taken with or without food, but it is better to take it at a fixed time.

Metronidazole + Ofloxacin is an antibiotic, having ofloxacin and metronidazole as its active ingredients. Both these medicines damage the DNA of the infection-causing bacteria, thus killing it by stopping its growth. This prevents the infection from spreading without making the bacteria resistant to further treatment.

• If your child develops diarrhea as a side effect, encourage them to drink plenty of water.
• Metronidazole + Ofloxacin may cause an altered taste. Eating citrus fruit or sipping plenty of water or fruit juice may help.
• Do not give any calcium, magnesium, iron, vitamin, or antacid to your child within 2 hours of taking Metronidazole + Ofloxacin as these can affect the absorption of the medicine.
• Conditions like common cold and flu are caused by viruses. Never use this medicine for such conditions.
• Your child must complete the entire course of antibiotics. Stopping too soon may cause the bacteria to multiply again, become resistant, or cause another infection.
• Discontinue Metronidazole + Ofloxacin and inform the doctor immediately if your child develops a rash, itchy skin, swelling of face and mouth, or has difficulty in breathing.
• Never save the medicine for future illnesses since its effectiveness in future infections cannot be guaranteed.

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Prathiba S, Kumar M. A Comparative Study of the Combination of Drugs - Amoxicillin with Metronidazole and Ofloxacin with Ornidazole In the Treatment of Dentoalveolar Abscess. Oral Health Case Rep. 2018;4:1. [Accessed 19 Jan. 2021] (online) Available from: