Methylcobalamin + Pregabalin
Introduction To Methylcobalamin + Pregabalin
Methylcobalamin + Pregabalin is a prescription medicine used for the treatment of neuropathic pain. It decreases pain by modulating calcium channel activity of the nerve cells. This medicine also protects nerve fibers and heal damaged nerve cells.
Methylcobalamin + Pregabalin is taken by mouth with or without food, preferably at bedtime. It is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor as this is a habit-forming medicine. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor.
Some common side effects of this medicine include dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. The side effects are mild in nature and get improve with time. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. It is important to inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.
Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Uses of Methylcobalamin + Pregabalin
- Treatment of Neuropathic pain
Benefits of Methylcobalamin + Pregabalin
Treatment of Neuropathic pain
Methylcobalamin + Pregabalin is a combination of medicines used to treat long-lasting (chronic)
pain caused by nerve damage due to diabetes, shingles or spinal cord injury.
It reduces pain and its associated symptoms such as mood changes, sleep
problems, and tiredness. Pregabalin, an active ingredient of this medicine, is
thought to work by interfering with pain signals that travel through the
damaged nerves and the brain. It also contains nutritional supplements that
improve nerve conduction. Taking Methylcobalamin + Pregabalin regularly will improve your
physical and social functioning and overall quality of life.
Side effects of Methylcobalamin + Pregabalin
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pregatal
- Dizziness
- Sleepiness
- Tiredness
- Uncoordinated body movements
How to use Methylcobalamin + Pregabalin
Take this medicine in the dose and duration as advised by your doctor. Methylcobalamin + Pregabalin may be taken with or without food, but it is better to take it at a fixed time.
How Methylcobalamin + Pregabalin works
Methylcobalamin + Pregabalin is a combination of two medicines: Methylcobalamin and Pregabalin. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibers and rejuvenates damaged nerve cells. Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Quick tips
- You have been prescribed Methylcobalamin + Pregabalin for treating and preventing nerve pain.
- Its side effects are usually mild and temporary.
- It may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- To lower the chances of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
- Avoid consuming alcohol when taking Methylcobalamin + Pregabalin, as it may cause excessive sleepiness.
- Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression or suicidal thoughts or behavior.
- Do not stop taking the medication suddenly without talking to your doctor.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Methylcobalamin + Pregabalin if I’m pregnant?
Methylcobalamin + Pregabalin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingCONSULT YOUR DOCTOR
Can I take Methylcobalamin + Pregabalin if I’m breastfeeding?
Methylcobalamin + Pregabalin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AlcoholUNSAFE
Is drinking alcohol while taking Methylcobalamin + Pregabalin safe?
Methylcobalamin + Pregabalin may cause excessive drowsiness with alcohol.
DrivingUNSAFE
Can I drive after taking Methylcobalamin + Pregabalin?
Methylcobalamin + Pregabalin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyCAUTION
Can I take Methylcobalamin + Pregabalin if I have/had kidney diseases?
Methylcobalamin + Pregabalin should be used with caution in patients with kidney disease. Dose adjustment of Methylcobalamin + Pregabalin may be needed. Please consult your doctor.
LiverSAFE IF PRESCRIBED
Can I take Methylcobalamin + Pregabalin if I have/had liver diseases?
Methylcobalamin + Pregabalin is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Methylcobalamin + Pregabalin may not be needed in these patients. Please consult your doctor.
Frequently Asked Questions
Q. What is Methylcobalamin + Pregabalin?
Methylcobalamin + Pregabalin is a combination of two medicines: Pregabalin and Methylcobalamin. This medicine is useful in the treatment of nerve pain (neuropathic pain). It calms the damaged or overactive nerves by acting on the brain, thereby decreasing the pain sensation. It also helps in the regeneration of damaged nerves in the body.
Q. Can I stop taking Methylcobalamin + Pregabalin when my pain is relieved?
No, you should not stop taking Methylcobalamin + Pregabalin even if your pain is relieved. Continue to take it as advised by your doctor. If you suddenly stop taking Methylcobalamin + Pregabalin, you may experience withdrawal symptoms such as anxiety, sleeping difficulties, nausea, pain and sweating. You may need to gradually taper the use of Methylcobalamin + Pregabalin before you stop the medication completely.
Q. How to manage weight gain associated with the use of Methylcobalamin + Pregabalin?
Methylcobalamin + Pregabalin can make you feel hungry which might make you eat more, thereby increasing your chances of putting on weight. However, preventing weight gain is easier than losing the increased weight. Try to eat a healthy balanced diet without increasing your portion sizes (per-meal intake). Do not eat food items that contain a lot of calories, such as soft drinks, oily food, chips, cakes, biscuits, and sweets. If you feel hungry between meals, avoid eating junk food and eat fruits, vegetables and low-calorie foods. Regular exercise will help prevent weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight.
Q. Can the use of Methylcobalamin + Pregabalin cause sleepiness or drowsiness?
Yes, Methylcobalamin + Pregabalin may make you feel drowsy or you may suddenly fall asleep during your daily activities. Sometimes, you might not even feel drowsy or have any other warning signs before you suddenly fall asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medicine affects you. Inform your doctor if you experience such episodes while you are taking this medicine.
Q. Are there any serious side effects associated with the use of Methylcobalamin + Pregabalin?
Serious side effects caused because of the use of Methylcobalamin + Pregabalin are uncommon and rare. However, it may cause serious side effects like allergic reaction, suicidal thoughts or swelling of limbs (hands, legs or feet). Stop taking Methylcobalamin + Pregabalin and contact your doctor if you have any signs of these serious side effects. Signs of an allergic reaction include swelling of your face, mouth, lips, gums, tongue and neck. Allergic reactions can also lead to trouble in breathing, skin rash, hives (raised bumps) or blisters. Pay attention to any changes, especially sudden changes in mood, behaviors, thoughts or feelings, or if you have suicidal thoughts.
Q. How long will the Methylcobalamin + Pregabalin take to act?
An initial benefit with Methylcobalamin + Pregabalin may be seen after 2 weeks of treatment. However, it may take around 2-3 months or more (in some patients) to see the full benefits.
Q. What if I forget to take Methylcobalamin + Pregabalin?
If you forget to take the scheduled dose of Methylcobalamin + Pregabalin and it is almost time for your next dose, skip the dose you missed and take your next dose at the scheduled time. Otherwise, take it as soon as you remember, and then go back to taking your medicine as you would normally. Do not take a double dose to make up for the dose you missed because this may increase the risk of unwanted side effects. If you are not sure what to do, consult your doctor about how to manage a situation like this.
Q. Will a higher than the recommended dose of Methylcobalamin + Pregabalin be more effective?
No, taking a higher than the recommended dose may not be more effective, rather it may increase the chances of having some serious side effects and toxicity. If you experience increased severity of your symptoms that are not relieved by the recommended doses, please consult your doctor for re- evaluation.
Q. Can I drink alcohol while taking Methylcobalamin + Pregabalin?
No, do not drink alcohol while taking Methylcobalamin + Pregabalin. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Methylcobalamin + Pregabalin.
Q. How often should I see the doctor ?
You may need to see your doctor regularly if you have started to take Methylcobalamin + Pregabalin. However, you must consult your doctor if the advised dosage of Methylcobalamin + Pregabalin does not improve your symptoms or you continue experiencing some unwanted side effects that affect your routine activities.
Q. Are there any special instructions regarding storage and disposal of this medicine?
Keep your tablets in the pack until it is time to take them. Store them in a cool dry place. Store them out of sight and reach of children. Unused medications should be disposed of in special ways to ensure that pets, children and other people cannot consume them.
References
Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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