Mephentermine

Mephentermine is used to raise blood pressure in hypotensive (low blood pressure) states, such as following spinal anesthesia. It increases the blood pressure rapidly by increasing the pumping capacity of the heart and narrowing blood vessels of the heart.

Mephentermine is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection. Your doctor may advise for regular monitoring of blood pressure while your taking this medicine.

It may cause side effects like high blood pressure, anxiety and insomnia (difficulty in sleeping). This medicine may not be suitable for some people. You must inform doctor if you are suffering from diabetes, liver, heart or kidney disease. Also let your doctor know about all the other medications that you are using regularly. This medicine is not usually recommended during pregnancy or breastfeeding, so always consult your doctor before taking it.

• Decreased blood pressure

Decreased blood pressure
Mephentermine is used to normalise decreased blood pressure (hypotension) which may occur due to administration of anesthesia in the spine during an operation. This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Termin

• Systemic hypertension (high blood pressure)
• Anxiety
• Insomnia (difficulty in sleeping)
• CNS stimulation

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Mephentermine is a sympathomimetic medicine. It helps to release a chemical messenger (adrenaline), which compresses the blood vessels. It also promotes the heart’s contractile ability to pump more blood. Hence, it works to increase your blood pressure.

• It is usually given as a slow injection into your veins by a doctor or healthcare professional.
• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
• Inform your doctor if you are taking or have recently taken medication to treat severe depression.

Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.

Drugs.com. Mephentermine Drug Interactions. [Accessed 19 Mar. 2019] (online) Available from: