Loperamide

Introduction To Loperamide

Loperamide is used in the treatment of diarrhea. It should not be used in patients with dysentery (diarrhea with blood).

Loperamide is taken with or without food in a dose and duration as advised by the doctor. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are headache, nausea, and constipation. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness.

Diarrhea can cause water loss and electrolyte imbalance, so drink plenty of fluids to help keep yourself hydrated. It is important to avoid this medicine if you have blood in your stool or if you are severely constipated.

Uses of Loperamide

  • Diarrhea

Benefits of Loperamide

Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Loperamide

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nelop

  • Constipation
  • Nausea
  • Headache
  • Stomach pain

How to use Loperamide

Take this medicine in the dose and duration as advised by your doctor. Loperamide may be taken with or without food, but it is better to take it at a fixed time.

How Loperamide works

Loperamide is an anti-diarrhoeal medication. It works by slowing down the contraction of the intestines thereby decreasing the speed at which the contents pass through it. This allows more time for reabsorption of fluids and nutrients, making the stools more solid and less frequent.

Quick tips

  • You have been prescribed Loperamide for the treatment of diarrhea.
  • Diarrhea can cause water loss and electrolyte imbalance. Drink plenty of fluids to help keep you hydrated.
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Loperamide if you have blood in your stool or if you are severely constipated.
  • Use caution while driving or doing anything that requires concentration as Loperamide can cause dizziness and sleepiness.
  • Stop taking the medication as soon as your symptoms are relieved.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Loperamide if I’m pregnant?

Loperamide may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingSAFE IF PRESCRIBED

Can I take Loperamide if I’m breastfeeding?

Loperamide is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Loperamide safe?

Loperamide may cause excessive drowsiness with alcohol.

sdsDrivingUNSAFE

Can I drive after taking Loperamide?

Loperamide may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

sdsKidneySAFE IF PRESCRIBED

Can I take Loperamide if I have/had kidney diseases?

Loperamide is safe to use in patients with kidney disease. No dose adjustment of Loperamide is recommended. However, inform your doctor if you have any underlying kidney disease.

sdsLiverCAUTION

Can I take Loperamide if I have/had liver diseases?

Loperamide should be used with caution in patients with liver disease. Dose adjustment of Loperamide may be needed. Please consult your doctor.

Frequently Asked Questions

Q. Is Loperamide safe?

Loperamide is relatively safe if used as recommended. In case of any side effects, consult your doctor.

Q. What is Loperamide used for?

Loperamide is used for treating short-term or long-term diarrhea, with or without any associated disease.

Q. Can Loperamide be used for IBS?

Loperamide may be used in few cases of IBS but please consult your doctor before its use.

Q. Can I take Loperamide with antibiotics, paracetamol, ibuprofen, omeprazole, ciprofloxacin, desmopressin, ritonavir, quinidine or cotrimoxazole?

Loperamide may be taken simultaneously with antibiotics, paracetamol, ibuprofen, omiprazole or ciprofloxacin. Loperamide might interact with desmopressin, ritonavir, quinidine or cotrimoxazole. Please consult your doctor before use

Q. Does Loperamide help in opiate withdrawal?

Loperamide is used in higher doses as a part of opiate withdrawal process. However, do consult your doctor regarding the same.

Q. Is Loperamide addictive?

No, Loperamide is a safe and non-addictive anti-diarrheal drug.

Q. Can Loperamide be used for stomach cramps, nausea, stomach flu, rota virus diarrhea and gas?

Loperamide may benefit few cases of stomach cramps or nausea associated with diarrhea. It is sometimes used for stomach flu, rota virus diarrhea. It is not used for gas. Please consult your doctor before taking the drug.

Q. Can I take Loperamide with cimetidine?

Cimetidine can decrease the metabolism of Loperamide, increase its blood levels and hence, increase its effects and side effects. Your dose of Loperamide may needs to be decreased. Consult your doctor prior to taking both the drugs together.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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