Lemborexant

Lemborexant helps treat sleep disorders (insomnia). It slows down the brain's activity and enables you to fall asleep and stay asleep longer, so you can get a better night's rest.

Take the drug orally in the dose, time, and way prescribed by the doctor. Prefer taking it right before retiring to bed with at least 7 hours remaining before the planned time of awakening. Do not take it if you fall asleep often at unexpected times (narcolepsy).

Avoid taking excessive dosage, as this medicine may have an addictive potential; therefore, use it for short periods as prescribed. Do not increase the prescribed dosage by yourself. If your condition worsens or does not improve within 7 to 10 days, report to your doctor immediately.

Never self-medicate at home, and do not start taking this medication on a regular basis without a confirmed diagnosis of a sleep disorder. Lemborexant may cause some side effects, such as daytime sleepiness, tiredness, and bad dreams during sleep. Consult the doctor right away in case of worrisome episodes.

Inform the doctor about your complete medical history, including the history of depression, mental illness, alcohol or drug abuse, daytime sleepiness, sudden onset of muscle weakness, lung or breathing problem, liver problem, pregnancy, breastfeeding, use of concomitant medicines, allergies, surgery, cardiac problem, or any other underlying medical condition. This information will help the doctor formulate your treatment plan better.

• Treatment of Insomnia

Treatment of Insomnia
Lemborexant helps treat insomnia (difficulty falling or staying asleep) in people who have problems related to their sleeping habits. Insomnia may cause you to wake up earlier than usual and you may find it difficult to go back to sleep. Lemborexant works by blocking the brain’s ability to keep you awake which helps you sleep. This relaxes the brain and makes you feel more energetic. It also helps you concentrate better and improves your quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dayvigo

• Drowsiness
• Headache
• Tiredness
• Nightmares
• Suicidal behaviors

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lemborexant may be taken with or without food, but it is better to take it at a fixed time.

Lemborexant blocks the action of orexin, a chemical that regulates the sleep signals in the brain and keeps you awake. Once orexin’s action is blocked, the brain doesn’t receive wake-up signals, which helps you sleep.

• Lemborexant can make you feel drowsy, therefore, patients, especially the elderly, may be at a higher risk of falls. Caution is advised.

• Take Lemborexant right before going to bed and only when you can stay in bed for a full night (at least 7 hours).

• Do not take Lemborexant with other medicines that can make you sleepy, unless your healthcare provider tells you to.

• Never share your medication with any other person who also has a sleep problem.

• Discuss it with your doctor if you develop unusual and strange thoughts or behavior while using Lemborexant.

• Stop taking the medication and inform your doctor if you experience complex sleep behaviors, including sleep-walking, sleep-driving, preparing and eating food, making phone calls, or having sex while not being fully awake.

• Make sure to regularly visit your doctor to check your progress and any side effects.

Lemborexant [FDA Label]. Woodcliff Lake, Eisai Inc.; 2019. [Accessed 06 Oct. 2022] (online) Available from:

Therapeutic Goods Administration (TGA), Government of Australia. Lemborexant [Product Information]. [Accessed 06 Oct. 2022] (online) Available from:

Neubauer DN. Lemborexant for insomnia. Current Psychiatry. 2020;19(11):43-49. [Accessed 06 Oct. 2022] (online) Available from: