Latanoprost

Latanoprost is a medicine used to reduce pressure in the eyes in people with glaucoma and ocular hypertension (high pressure in the eye). If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood.

Latanoprost is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. If you wear contact lenses, make sure you remove them before instilling and wait for at least 15 minutes before putting them back.

The most common side effects include eyelashes changes, eye pain and sensitivity to light. It may also cause blurred vision, dryness in the eye, a gradual change in color of the eye, and other rare effects. If you get any side effects, talk to your doctor. Your doctor may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short-term side effect. Do not use this medicine if you are pregnant or trying to become pregnant, or if you are breastfeeding.

• Glaucoma
• Ocular hypertension

Glaucoma
Latanoprost is a medicine used to reduce pressure in your eyes (ocular hypertension). This pressure can lead to an illness called glaucoma. If the pressure in your eye is too high, it can damage your sight. This medicine works by helping the fluid to flow from inside the eye into your bloodstream. It may be used alone or with other eye drops. Do not use it too often as that can make it less effective. You should only use it in the affected eye and take it regularly as prescribed by your doctor. If you stop taking it, the pressure in your eye will not be controlled. This could lead to a loss of sight.

Ocular hypertension
Latanoprost belongs to a group of medicines called prostaglandin analogue. It is used to reduce pressure in your eyes. It increases the flow of fluid from inside the eye into the bloodstream thereby lowering the increased eye pressure. If the pressure in your eye is too high, it can damage your sight. You should only use it in the affected eye and take it regularly as prescribed by your doctor. If you stop taking it, the pressure in your eye will not be controlled.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ioptame

• Eyelash changes
• Eye pain
• Increased sensitivity to light
• Burning sensation in eye
• Eye itching
• Foreign body sensation
• Itching
• Stinging in the eyes
• Conjunctival hyperemia

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.

Latanoprost is a prostaglandin analogue. It works by increasing the outflow of aqueous humor, thereby lowering the increased eye pressure.

• Latanoprost helps lower high pressure in the eye and reduces the risk of vision loss.
• For best results, put one drop once a day in the evening/night in the affected eye(s).
• Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
• Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
• Latanoprost may cause brown pigmentation of the iris. This discoloration may be permanent.
• Your eyelashes may become more dense and eyelid skin may darken. These changes should disappear after discontinuing Latanoprost.

Smyth EM, Grosser T, FitzGerald GA. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 952.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 781.

Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 328.

Latanoprost. Romford, Essex: Martindale Pharma; 2010 [revised 22 Jan. 2019]. [Accessed 04 Apr. 2019] (online) Available from:

Latanoprost. Puurs, Belgium: Pfizer Manufacturing; 1996 [revised Jun. 2014]. [Accessed 04 Apr. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from: