Itopride + Pantoprazole

Itopride + Pantoprazole is a combination medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms of acidity such as heartburn, stomach pain, or irritation. It also neutralizes the acid and promotes easy passage of gas to reduce stomach discomfort.

Itopride + Pantoprazole is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are diarrhea, stomach pain, headache, flatulence, and increased saliva production. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.

Before you start taking this medicine it is important to inform your doctor if you are suffering from kidney disease. You should also tell your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Gastroesophageal reflux disease (Acid reflux)
• Peptic ulcer disease

Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in which there is an excess production of acid in the stomach. Itopride + Pantoprazole reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You should take it exactly as it is prescribed for it to be effective. Some simple lifestyle changes can help reduce the symptoms of GERD. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

Peptic ulcer disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop in the inner lining of the stomach or gut (intestine). Itopride + Pantoprazole reduces the amount of acid your stomach makes which prevents further damage to the ulcer as it heals naturally. You may be given other medicines along with this medicine depending on what caused the ulcer. You need to keep taking the medicine as it is prescribed for it to be effective, even if the symptoms seem to disappear.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pantogel-IT

• Diarrhea
• Stomach pain
• Headache
• Flatulence
• Dizziness
• Increased saliva production

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Itopride + Pantoprazole is to be taken empty stomach.

Itopride + Pantoprazole is a combination of two medicines: Pantoprazole and Itopride. Pantoprazole is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn. Itopride is a prokinetic which works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

• You have been prescribed Itopride + Pantoprazole for the treatment of acidity and heartburn.
• Take it one hour before the meal, preferably in the morning.
• It is a well-tolerated medicine and provides relief for a long time.
• Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
• Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
• Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.

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Itopride. [Accessed 12 Apr. 2019] (online) Available from:

Pantoprazole sodium sesquihydrate. Wooburn Green, High Wycombe: Takeda UK Ltd.; 2009 [revised 26 Oct. 2018]. [Accessed 12 Apr. 2019] (online) Available from:

Itopride. Abbott; 2008. [Accessed 12 Apr. 2019] (online) Available from: