Isoxsuprine

Isoxsuprine is a vasodilator and uterine relaxant. It is used in the treatment of premature labor (when the uterus starts contracting for birth too early than usual). It is also helpful in the treatment of peripheral vascular diseases.

Isoxsuprine can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a glass of water. You should take this medicine for as long as it is prescribed for you.

Dizziness is the most common side effect of the medicine. If these bother you or appear serious, let your doctor know. To lower the chance of dizziness, you must rise slowly, if getting up from a sitting or lying position or avoid driving or attention requiring activities.

Before taking the medicine, tell your doctor if you have ever had heart problems or bleeding disorders. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. You must avoid taking part in any strenuous or stressful activities to prevent premature labor.

• Treatment of Premature Labor
• Treatment of Peripheral vascular disease

Treatment of Premature Labor
Isoxsuprine prevents abnormal contractions of uterus muscles and relaxes them. It widens blood vessels to help increase blood flow and improve circulation to the smooth muscles of the uterus. This prevents premature labor and miscarriage. Take it as prescribed and follow your doctor’s instructions carefully to get maximum benefit.

Treatment of Peripheral vascular disease
Peripheral vascular disease refers to the condition of disturbed blood circulation in blood vessels. Isoxsuprine helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of X-Ride

• Dizziness
• Palpitations

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isoxsuprine may be taken with or without food, but it is better to take it at a fixed time.

Isoxsuprine is a beta-adrenergic agonist. It works by preventing the contractions of the smooth muscles in the uterus. Thus, it relaxes the uterus to prevent premature labor. It also helps in widening blood vessels to increase blood flow, thereby improving blood circulation to certain parts of the body (such as the hands/feet, brain). Therefore, it also treats peripheral vascular disease.

• You have been prescribed Isoxsuprine for the treatment of premature labor.
• It may also be used in the treatment of peripheral vascular diseases.
• Avoid stress or any kind of strenuous activity to prevent premature labor
• Isoxsuprine may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Inform your doctor if you experience a rash or irregular heartbeats or if you have bleeding disorders, glaucoma, or heart disease.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 747-48.

DailyMed. Isoxsuprine. [Accessed 03 Apr. 2019] (online) Available from:

Drugs.com. Isoxsuprine. [Accessed 03 Apr. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from: