Hydralazine

Hydralazine belongs to a class of drugs known as vasodilators. It is used for the treatment of severe or life-threatening hypertension (high blood pressure), when the drug cannot be given orally or when there is an urgent need to lower blood pressure in hospitalised patients.

Hydralazine works by relaxing and enlarging certain small blood vessels so that blood flows through them more easily. It is given under the supervision of a healthcare professional and should not be self administered. Certain patients (especially those with marked kidney damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes.

Hydralazine should be used immediately after opening. It should not be added to other solutions. It may discolor upon contact with metal; discolored solutions should be discarded. Some of the common side effects of this medicine are headache, loss of appetite, nausea, vomiting, diarrhea and increased heart rate. Please contact your doctor if these side effects do not resolve or persist for a longer duration.

• Hypertension (high blood pressure)

Hypertension (high blood pressure)
Hydralazine is a medicine used to treat severe or life-threatening hypertension (high blood pressure). It increases the flow of blood and oxygen to the heart and other organs by relaxing blood vessels, thereby, lowering your blood pressure. It is usually given as a slow injection by a doctor or healthcare professional.

If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. It must be taken regularly as prescribed to be effective.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dralgeen

• Diarrhea
• Headache
• Increased heart rate
• Loss of appetite
• Nausea
• Palpitations
• Vomiting

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Hydralazine is a potassium channel opener. It works by relaxing blood vessels which lowers blood pressure and allows more blood and oxygen to reach the heart and other organs.

• Hydralazine is usually given as a slow injection into your veins by a doctor or healthcare professional.

• It may cause dizziness. Do not drive or perform activities that require mental focus until you know how Hydralazine affects you.

• Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

• Inform your doctor about taking this medicine before undergoing any surgical procedure.

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 779-81.

Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 178-79.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 658-59.

Hydralazine Hydrochloride Injection. Shirley, New York: American Regent Inc.; 2013. [Accessed 22 Jan. 2019] (online) Available from:

Drugs.com. Hydralazine Pregnancy and Breastfeeding Warnings. [Accessed 18 Mar. 2019] (online) Available from:

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 18 Mar. 2019] (online) Available from: