Human Gamma Globulin

Human Gamma Globulin consists of proteins of liquid human serum, containing the antibodies of healthy adults. This is used to strengthen the body's natural defense system (immune system) to lower the risk of infection in persons with a weakened immune system.

This is given by injection under the skin or slowly into a vein as directed by your doctor. This is made from healthy human blood that has a high level of certain defensive substances (antibodies), which help fight infections. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenic purpura-ITP).

Your healthcare professional will start the medication slowly while monitoring you closely. You may experience side effects such as headache, nausea, chills, fatigue, fever, upper abdominal pain, diarrhea, back pain, injection site reactions, excessive sweating, and flushing. Tell your doctor if you are bothered by any of these side effects.

• Prevention of Infections

Prevention of Infections
Human Gamma Globulin strengthens or boost the immune system and lower the risk of infection in persons with a weakened immune system. It works by producing antibodies against foreign substances thereby fighting against infection. It is also used to increase the blood count (platelets) in persons with a certain blood disorder (idiopathic thrombocytopenic purpura-ITP). This helps stop bleeding and promote the formation of blood clots. Human Gamma Globulin should be administered only by or under the supervision of your doctor.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Immunorel

• Headache
• Nausea
• Chills
• Fatigue
• Fever
• Upper abdominal pain
• Diarrhea
• Back pain
• Injection site reactions (pain, swelling, redness)
• Sweating
• Flushing (sense of warmth in the face, ears, neck and trunk)

Your doctor or nurse will give you this medicine. Kindly do not self- administer.

Human gamma globulin contains antibodies, mainly immunoglobulin G (IgG), to various bacteria and viruses present in the general population such as hepatitis A, measles, mumps, rubella and varicella. It has a distribution of IgG subclasses that is very close to that of the normal human plasma. It is therefore, used to provide passive immunisation against such diseases.

• Human Gamma Globulin is prescribed to boost the immune system and prevent infection in people with low immunity.
• Human Gamma Globulin should be injected slowly in order to prevent severe allergic reactions.
• Inform your doctor if you have a cold or chest infection on the day of treatment. This will prevent any kind of reactions on your body.
• Inform your doctor if you have diabetes, kidney disease, high blood pressure or heart disease.
• If you get shortness of breath during or within several hours of your treatment, tell your doctor immediately.
• Human Gamma Globulin might interfere with certain virus vaccines such as measles, rubella, mumps, varicella, and yellow fever. Inform your doctor with complete information about your vaccinations.

ScienceDirect. Gamma globulin. [Accessed 04 Apr. 2019] (online) Available from:

Immune Globulin Intravenous [Human]. Elstree, Hertfordshire: Human Gamma Globulin; 2009 [revised Jul. 2015]. [Accessed 04 Apr. 2019] (online) Available from: