Glycerin + Mannitol

Introduction To Glycerin + Mannitol

Glycerin + Mannitol is a combination of two medicines. It is used in the treatment of cerebral edema. It works by drawing water out of the tissues in the brain and decreases swelling around the brain.

Glycerin + Mannitol is given as an injection under the supervision of a healthcare professional. Do not try to self administer the injection until you know how to inject it. Your doctor will decide the exact amount of dose, hence follow your doctor advice while taking the medicine.

The medicine is generally safe to use with no common side effects. Take caution while taking medicine if you are suffering from liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Glycerin + Mannitol

  • Cerebral edema (accumulation of excessive fluid in the brain)

Benefits of Glycerin + Mannitol

Cerebral edema (accumulation of excessive fluid in the brain)
Symptoms of brain swelling (cerebral edema) include headache, dizziness, nausea, numbness or weakness, loss of coordination or balance, loss of the ability to see or speak, seizures (fits), memory loss, incontinence, or altered level of consciousness. Glycerin + Mannitol decreases brain volume by decreasing overall water content in the brain. This helps to reduce the accumulation of excessive fluid in the brain. It helps to relieve these symptoms effectively within a short duration of time and prevents further complications.

Side effects of Glycerin + Mannitol

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Glitol

  • No common side effects seen

How to use Glycerin + Mannitol

Your doctor or nurse will give you this medicine. Kindly do not self- administer.

How Glycerin + Mannitol works

Glycerin + Mannitol is a combination of two medicines: Glycerin and Mannitol which treat increased pressure in the skull/brain. Mannitol is an osmotic diuretic which draws water out of tissues in the brain and decreases swelling around the brain. Addition of Glycerin prevents the swelling from coming back which may possibly occur with plain Mannitol.

Quick tips

  • Glycerin + Mannitol is used for the treatment of cerebral edema (swelling in the brain).
  • The heart rate and health of the patient should be carefully evaluated before administering Glycerin + Mannitol.
  • Urinary output, fluid balance, central venous pressure, and electrolyte balance (in particular serum sodium and potassium levels) should be carefully monitored.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Glycerin + Mannitol if I’m pregnant?

Glycerin + Mannitol may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingSAFE IF PRESCRIBED

Can I take Glycerin + Mannitol if I’m breastfeeding?

Glycerin + Mannitol is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

sdsAlcoholCONSULT YOUR DOCTOR

Is drinking alcohol while taking Glycerin + Mannitol safe?

It is not known whether it is safe to consume alcohol with Glycerin + Mannitol. Please consult your doctor.

sdsDrivingSAFE

Can I drive after taking Glycerin + Mannitol?

Glycerin + Mannitol does not usually affect your ability to drive.

sdsKidneySAFE IF PRESCRIBED

Can I take Glycerin + Mannitol if I have/had kidney diseases?

Glycerin + Mannitol is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Glycerin + Mannitol may not be needed in these patients. Please consult your doctor.

sdsLiverCONSULT YOUR DOCTOR

Can I take Glycerin + Mannitol if I have/had liver diseases?

There is limited information available on the use of Glycerin + Mannitol in patients with liver disease. Please consult your doctor.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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