Gliclazide + Metformin + Pioglitazone

Gliclazide + Metformin + Pioglitazone is an anti-diabetic medicine that is used to treat type 2 diabetes mellitus. It helps control blood sugar levels in adults with diabetes.

Gliclazide + Metformin + Pioglitazone should be taken with food, preferably at the same time each day. Your doctor will decide what dose is best for you and this may change from time to time based on your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Gliclazide + Metformin + Pioglitazone is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of low blood glucose levels (sweating, dizziness, headache) and know how to deal with them. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include nausea, taste changes, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and upper respiratory tract infections. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

• Treatment of Type 2 diabetes mellitus

Treatment of Type 2 diabetes mellitus
Insulin is a hormone that is required to lower the amount of sugar in your body. But if you have type 2 diabetes, your body will produce less amount of insulin. Gliclazide + Metformin + Pioglitazone allows the body to make better use of the lower amount of insulin to control your blood glucose level. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Reclimet-PG

• Hypoglycemia (low blood glucose level)
• Dizziness
• Headache
• Nausea
• Vomiting
• Diarrhea
• Flatulence
• Upper respiratory tract infection
• Bronchitis (inflammation of the airways)
• Anemia (low number of red blood cells)
• Edema (swelling)

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Gliclazide + Metformin + Pioglitazone is to be taken with food.

Gliclazide + Metformin + Pioglitazone is a combination of three antidiabetic medicines: Gliclazide, Pioglitazone and Metformin. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Gliclazide is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Pioglitazone is a thiazolidinedione which increases insulin sensitivity. Metformin is a biguanide. It works by lowering glucose production in the liver, delaying glucose absorption from intestines and further increasing the body's sensitivity to insulin.

• Gliclazide + Metformin + Pioglitazone is a combination of three medicines that provides better blood sugar control than either medicine alone.

• You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Gliclazide + Metformin + Pioglitazone.

• Take it with food to lower your chance of having an upset stomach.

• Monitor your blood sugar level regularly while you are taking this medicine.

• It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.

• Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.

• Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

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