Gentamicin

Gentamicin is an antibiotic used to prevent or treat a wide variety of bacterial infections. This may include infections of the urinary tract, bones and joints, lungs (e.g., pneumonia), brain (e.g., meningitis), sepsis, and some others. However, it is not effective for gonorrhea.

Gentamicin is also widely used in hospitalized patients to prevent infections. It works by stopping the growth of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor may shift you to another antibiotic after culture reports become available. It should be used regularly at evenly spaced time intervals as prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

This medicine may lead to kidney damage and hearing loss as side effects in some patients. Therefore, it is important to follow all the instructions given by your doctor while using this medicine. It may also cause balance disorder (loss of balance) and injection site pain in some people.

Your doctor may monitor you with regular kidney function tests or hearing tests during treatment. Some patients may also be advised to get blood levels of this medicine measured. Before using this medicine, inform your doctor if you are pregnant, planning to become, or breastfeeding.

• Treatment of Bacterial infections

Treatment of Bacterial infections
Gentamicin is the injection form of an antibiotic medicine that stops the growth of the infection causing bacteria in your body. It is often injected by a doctor or a nurse either into a vein or a muscle. This medicine is used to treat many different types of infections such as urinary tract, bones and joints, lungs (eg. pneumonia), brain, blood, and some others. This medicine usually makes you feel better within a few days. Follow your doctor's instructions carefully to get maximum benefit.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Alpagen

• Hearing loss
• Kidney damage
• Balance disorder (loss of balance)
• Injection site pain

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Gentamicin is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions.

MacDougall C, Chambers HF. Aminoglycosides. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1515-16.

Chambers HF, Deck DH. Aminoglycosides & Spectinomycin. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 811-12.

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 620-22.

Gentamicin. Horizon, Honey Lane: Hospira UK Limited; 5 Feb. 1998 [revised May. 2018]. [Accessed 31 Mar. 2019] (online) Available from:

Drugs.com. Gentamicin. [Accessed 31 Mar. 2019] (online) Available from:

Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 31 Mar. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from: