Flupirtine

Flupirtine is a pain relieving medicine. It is used to treat acute and chronic pain associated with various conditions such as muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. It is not recommended for use in patients less than 18 years of age.

Flupirtine can be taken with or without food. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as this will make the medicine less effective.

Some of the common side effects of this medicine include fatigue, dizziness, drowsiness, nausea, dryness in mouth, and abdominal bloating. If any of these side effects do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

To make sure it is safe for you, before taking this medicine, let your doctor know if you have any medical conditions or disorders. You should also tell your doctor all the other medicines you are using or taking. Pregnant and breastfeeding women should consult their doctors before using this medicine.

• Pain relief

Pain relief
Flupirtine helps relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like muscle pain, headache, nerve pain, postoperative pain, and menstrual cramps. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This medicine helps one go about their daily activities more easily and have a better, more active, quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ftp

• Fatigue
• Dizziness
• Nausea
• Dryness in mouth
• Tremors
• Heartburn
• Vomiting
• Abdominal pain
• Constipation
• Loss of appetite
• Depression
• Headache
• Abdominal discomfort
• Sleep disturbance
• Increased sweating
• Restlessness
• Nervousness
• Flatulence
• Diarrhea

Take this medicine in the dose and duration as advised by your doctor. Flupirtine may be taken with or without food, but it is better to take it at a fixed time.

Flupirtine decreases the perception of pain by blocking the transmission of pain signals to the brain.

• Flupirtine is given when pain killers (NSAIDs) cannot be given due to gastric damage caused by them.

• Inform your doctor before starting Flupirtine if

  • You have an underlying liver disease
  • You take alcohol regularly
  • You are pregnant or planning to get pregnant or breastfeeding

• Get your liver function tests done before starting Flupirtine and follow up tests every week while you are taking the medicine.

• Stop taking Flupirtine and immediately inform your doctor if you get any symptoms of liver disease like nausea, vomiting, stomach pain or yellow colored urine.

Sciencedirect. Flupirtine. [Accessed 02 Apr. 2019] (online) Available from:

Harish S, Bhuvana K, Bengalorkar GM, et al. Flupirtine: Clinical pharmacology. J Anaesthesiol Clin Pharmacol. 2012;28(2):172-7. [Accessed 24 Jan. 2019] (online) Available from:

Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from: