Estriol

Estriol is identical to a female hormone, estrogen. It is used to treat symptoms associated with menopause. This topical preparation helps to treat vaginal burning, dryness and itching caused due to lack of estrogen.

You should use Estriol in the way your doctor advises. It may depend on whether you have had any kind of hormonal replacement treatment (HRT) before. Even if your symptoms improve, you should continue the treatment as it has been prescribed.

When you start using this medicine you may experience vaginal irritation or itching. This usually goes away if you continue using it. You may also get pain in your abdomen, a genital rash, headache and vaginal thrush (candidiasis). Tell your doctor if you experience bleeding in your vagina. Your doctor may give you an alternative medicine.

Before using this medicine you should tell your doctor if you have unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. Once you have started using this medicine you should have regular check-ups to discuss the benefits of your treatment. It should not interact with any other medicines. It is not usually recommended during pregnancy or breastfeeding.

• Menopausal symptoms

Menopausal symptoms
Estriol is a female hormone, identical to a hormone that your body makes naturally called estrogen. When you have too little of this hormone (after menopause), the vaginal wall can become thin and dry. This can make sexual intercourse painful and you may get vaginal infections. Estriol will help relieve vaginal dryness, inflammation, and itching that may occur after menopause. It may take a few weeks before you notice an improvement so keep using the medicine even if you think it is not working to get the full benefits. It has very few side effects and will also make you less likely to have vaginal or urinary infections.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Evalon

• Vaginal irritation
• Vaginal itching

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream by using applicator. Wash your hands after applying.

Estriol contains oestrogen (female sex hormone). It works by delivering estrogens directly into the vagina to relieve vaginal symptoms of menopause such as dryness, burning, irritation, and painful sexual intercourse.

• It can be applied to the external vaginal area or inserted into the vagina using the applicator provided.
• It does not expose the rest of your body to the medicine, thereby avoiding side effects that happen more often with pills.
• Do not have sex right after using Estriol as some of the medicine can be absorbed into your partner's skin.
• Inform your doctor if you experience any vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while using this medicine.
• Do not use Estriol if you are pregnant or breastfeeding, have a history of blood clots or heart diseases.

Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 701-702.

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Estriol. Dublin, Ireland: Aspen; 1982 [revised 16 Dec. 2016]. [Accessed 23 Jan. 2019].(online) Available from:

Estriol. Swords, Ireland: Organon (Ireland) Ltd.; 2017. [Accessed 03 Apr. 2019] (online) Available from: