Duloxetine + Methylcobalamin
Introduction To Duloxetine + Methylcobalamin
Duloxetine + Methylcobalamin is a combination of two medicines used to treat neuropathic pain. It works by protecting the nerve fibres against damage, repairing the damaged nerves. This way it effectively relieves the pain sensation and also elevates the mood.
Duloxetine + Methylcobalamin may be taken with or without food. However, it is advised to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration advised by your doctor. If you miss a dose of this medicine, take it as soon as you remember. Finish the full course of the treatment even if you feel better. It is important not to stop taking this medicine suddenly.
Some common side effects of this medicine include nausea, constipation, headache, insomnia (difficulty in sleeping), ejaculation disorder, erectile dysfunction, and low sexual desire. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.
You should avoid alcohol while taking Duloxetine + Methylcobalamin, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.
Uses of Duloxetine + Methylcobalamin
- Neuropathic pain
Benefits of Duloxetine + Methylcobalamin
Neuropathic pain
Duloxetine + Methylcobalamin is a combination of medicines used to treat long-lasting (chronic)
pain caused by nerve damage due to diabetes, shingles, or spinal cord injury.
It reduces pain and its associated symptoms such as mood changes, sleep
problems, and tiredness. It is thought to work by interfering with pain
signals that travel through the damaged nerves and the brain. It also contains
nutritional supplements that are essential for improving nerve conduction.
Duloxetine + Methylcobalamin regularly will improve your physical and social functioning and
overall quality of life. It takes a few weeks to work so you need to take it
regularly even if you feel it is not doing any good. Once your symptoms have
gone you should still keep taking the medicine until your doctor advises you
to stop.
Side effects of Duloxetine + Methylcobalamin
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duzela M
- Nausea
- Constipation
- Headache
- Insomnia (difficulty in sleeping)
- Ejaculation disorder
- Erectile dysfunction
- Low sexual desire
How to use Duloxetine + Methylcobalamin
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Duloxetine + Methylcobalamin may be taken with or without food, but it is better to take it at a fixed time.
How Duloxetine + Methylcobalamin works
Duloxetine + Methylcobalamin is a combination of two medicines: Duloxetine and methylcobalamin. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) which works by increasing the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Methylcobalamin is a form of vitamin B which helps in the production of myelin, a substance that protects nerve fibres and rejuvenates damaged nerve cells. Together, they relieve neuropathic pain (pain from damaged nerves).
Quick tips
- Duloxetine + Methylcobalamin is used to treat certain types of long-lasting pain caused by damage to nerves.
- It may ease the pain within a few days but it may take 2-3 weeks before you see maximum benefit.
- Inform your doctor if you are taking any other pain-relieving medicines.
- Along with taking this medicine, your doctor might advise you to undergo physiotherapy to get relief from pain.
- You might experience low sexual desire after taking Duloxetine + Methylcobalamin, talk to your doctor if it troubles you.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Duloxetine + Methylcobalamin if I’m pregnant?
Duloxetine + Methylcobalamin may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingCONSULT YOUR DOCTOR
Can I take Duloxetine + Methylcobalamin if I’m breastfeeding?
Duloxetine + Methylcobalamin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
AlcoholUNSAFE
Is drinking alcohol while taking Duloxetine + Methylcobalamin safe?
It is unsafe to consume alcohol with Duloxetine + Methylcobalamin.
DrivingUNSAFE
Can I drive after taking Duloxetine + Methylcobalamin?
Duloxetine + Methylcobalamin may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
KidneyCAUTION
Can I take Duloxetine + Methylcobalamin if I have/had kidney diseases?
Duloxetine + Methylcobalamin should be used with caution in patients with severe kidney disease. Dose adjustment of Duloxetine + Methylcobalamin may be needed. Please consult your doctor. Dose adjustment is not recommended in patients with mild and moderate kidney disease.
LiverUNSAFE
Can I take Duloxetine + Methylcobalamin if I have/had liver diseases?
Duloxetine + Methylcobalamin is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.
References
Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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