Domperidone + Omeprazole
Introduction To Domperidone + Omeprazole
Domperidone + Omeprazole is a prescription medicine used to treat gastroesophageal reflux disease (Acid reflux) and peptic ulcer disease by relieving the symptoms such as heartburn, stomach pain, or irritation. It also neutralizes the acid in the stomach and promotes easy passage of gas to reduce stomach discomfort.
Domperidone + Omeprazole is taken without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.
Most common side effects are diarrhea, stomach pain, dryness in mouth, headache, and flatulence. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any side effects. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness. Lifestyle modifications like having cold milk and avoiding hot tea, coffee, spicy food or chocolate can help you to get better results.
Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have liver diseases so that your doctor can prescribe a suitable dose for you.
Uses of Domperidone + Omeprazole
- Treatment of Gastroesophageal reflux disease (Acid reflux)
- Treatment of Peptic ulcer disease
Benefits of Domperidone + Omeprazole
Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition in
which there is an excess production of acid in the stomach. Domperidone + Omeprazole reduces
the amount of acid your stomach makes and relieves the pain associated with
heartburn and acid reflux. You should take it exactly as it is prescribed for
it to be effective.
Some simple lifestyle changes can help reduce the symptoms of GERD. Think
about what foods trigger heartburn and try to avoid them; eat smaller, more
frequent meals; try to lose weight if you are overweight and try to find ways
to relax. Do not eat within 3-4 hours of going to bed.
Treatment of Peptic ulcer disease
Peptic ulcer disease is a condition in which painful sores or ulcers develop
in the inner lining of the stomach or gut (intestine). Domperidone + Omeprazole reduces the
amount of acid your stomach makes which prevents further damage to the ulcer
as it heals naturally. You may be given other medicines along with this
medicine depending on what caused the ulcer. You need to keep taking the
medicine as it is prescribed for it to be effective, even if the symptoms seem
to disappear.
Side effects of Domperidone + Omeprazole
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Omezip-D
- Diarrhea
- Stomach pain
- Dryness in mouth
- Headache
- Flatulence
How to use Domperidone + Omeprazole
Take this medicine in the dose and duration as advised by your doctor. Domperidone + Omeprazole is to be taken empty stomach.
How Domperidone + Omeprazole works
Domperidone + Omeprazole is a combination of two medicines: Domperidone and Omeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Omeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Quick tips
- You have been prescribed Domperidone + Omeprazole for the treatment of acidity and heartburn.
- Take it one hour before the meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
Safety Advice
PregnancyCONSULT YOUR DOCTOR
Can I take Domperidone + Omeprazole if I’m pregnant?
Domperidone + Omeprazole may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
BreastfeedingSAFE IF PRESCRIBED
Can I take Domperidone + Omeprazole if I’m breastfeeding?
Domperidone + Omeprazole is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
AlcoholCAUTION
Is drinking alcohol while taking Domperidone + Omeprazole safe?
Caution is advised when consuming alcohol with Domperidone + Omeprazole. Please consult your doctor.
DrivingUNSAFE
Can I drive after taking Domperidone + Omeprazole?
Domperidone + Omeprazole may cause side effects which could affect your ability to drive. Domperidone + Omeprazole may cause dizziness and visual disturbances. This may affect your driving ability.
KidneyCAUTION
Can I take Domperidone + Omeprazole if I have/had kidney diseases?
Domperidone + Omeprazole should be used with caution in patients with kidney disease. Dose adjustment of Domperidone + Omeprazole may be needed. Please consult your doctor.
LiverCAUTION
Can I take Domperidone + Omeprazole if I have/had liver diseases?
Domperidone + Omeprazole should be used with caution in patients with liver disease. Dose adjustment of Domperidone + Omeprazole may be needed. Please consult your doctor. Use of Domperidone + Omeprazole is not recommended in patients with moderate and severe liver disease.
Frequently Asked Questions
Q. Is it safe to use Domperidone + Omeprazole?
Yes, Domperidone + Omeprazole is safe for most of the patients. However, in some patients it may cause common side effects like diarrhea, stomach pain, flatulence, dryness in the mouth, dizziness, headache and other uncommon and rare side effects. Inform your doctor if you experience any persistent problem while taking this medicine.
Q. What are the contraindications of Domperidone + Omeprazole?
The use of Domperidone + Omeprazole is considered to be harmful in patients with a known hypersensitivity to omeprazole or domperidone or any other inactive ingredients present in the medicine. Cautious use is advised in patients with underlying kidney or liver disease.
Q. What is the best time to take Domperidone + Omeprazole?
It is best to take the medicine daily before breakfast or on an empty stomach.
Q. Can the use of Domperidone + Omeprazole cause abnormal heartbeat?
Yes, the use of Domperidone + Omeprazole can cause an increased risk of irregular heartbeat (serious arrhythmias). These are serious side effects but the chances that it may happen is very low. The risk may be slightly higher in those who are more than 60 years of age.
Q. Does the use of Domperidone + Omeprazole lead to dry mouth?
Yes, the use of Domperidone + Omeprazole can cause dry mouth. Dryness of mouth occurs due to Domperidone, which is present in this combination. If you experience dry mouth, drink plenty of water. Take regular sips of water during the day and keep some water on your bedside at night. Cut down the intake of alcohol and avoid smoking. If you have dry mouth, try to use alcohol-free mouthwash as its use increases the risk of tooth decay.
Q. What is the recommended storage condition for Domperidone + Omeprazole?
Keep this medicine in the container or pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
References
Written By:
Dr Advikka Ridhy
MBBS
RMO, Aster MIMS
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