Cyproterone + Ethinyl Estradiol

Introduction To Cyproterone + Ethinyl Estradiol

Cyproterone + Ethinyl Estradiol is a combination of two hormonal medicines used to treat symptoms of polycystic ovary syndrome (PCOS) such as excessive hair growth (hirsutism), acne, and irregular periods. It also works as a contraceptive, hence avoid using any other contraceptive pill.

Cyproterone + Ethinyl Estradiol can be taken with or without food. Take it at the same time every day as it will help you remember to take it. The dose and duration will depend on what you are being treated for, but you should always complete a full course of this medicine as prescribed by your doctor.

The most common side effects of this medicine include nausea, stomach pain, headache, weight gain, and breast pain. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Consult your doctor if you frequently experience spotting or brown discharge in the middle of the cycle. You must also consult your doctor if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain or changes in vision.

Do not continue with the medicine and consult with the doctor if your periods do not start within a week of the treatment. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Avoid the use of medicine if you are pregnant or breastfeeding.

Uses of Cyproterone + Ethinyl Estradiol

  • Treatment of Polycystic ovarian syndrome (PCOS)

Benefits of Cyproterone + Ethinyl Estradiol

Treatment of Polycystic ovarian syndrome (PCOS)
Women with Polycystic ovarian syndrome (PCOS) have high levels of male hormones called androgens, that are responsible for irregular menstrual cycles (periods), excessive hair growth and acne. Cyproterone + Ethinyl Estradiol is a combination medicine that helps in regulating the production of these androgens as well as periods in females. This also helps in treating excessive hair growth (hirsutism) and acne effectively. Take it as prescribed by the doctor. Do not skip any doses and follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Cyproterone + Ethinyl Estradiol

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pinkeva

  • Nausea
  • Stomach pain
  • Headache
  • Weight gain
  • Breast pain
  • Mood changes

How to use Cyproterone + Ethinyl Estradiol

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cyproterone + Ethinyl Estradiol may be taken with or without food, but it is better to take it at a fixed time.

How Cyproterone + Ethinyl Estradiol works

Cyproterone + Ethinyl Estradiol is a combination of two hormonal medicines: Cyproterone and Ethinyl Estradiol which treats PCOS symptoms such as acne, excessive hair growth (hirsutism) and irregular periods. Cyproterone works by blocking the overproduction of androgens (male hormones) in the ovaries, thereby reducing unwanted hair growth and acne. Ethinyl Estradiol enhances the effect of Cyproterone by reducing the amount of androgens in the blood. Together, they also regularize the menstrual cycle in PCOS.

Quick tips

  • Take your pill at the same time every day to help you remember to take it.
  • Do not use Cyproterone + Ethinyl Estradiol if you are obese, over 50, smoke, on prolonged bed rest or have a history of blood clots.
  • Stop taking it and inform your doctor if you notice unexplained swelling and pain in your limbs, shortness of breath, chest pain or changes in vision.
  • You may experience vaginal spotting (blood stain) or breakthrough bleeding while taking Cyproterone + Ethinyl Estradiol. This is temporary, inform your doctor if it lasts longer.
  • If your period fails to come within a week after completing your course, do not start the next course, before consulting your doctor.
  • It works as a contraceptive. So, do not use any additional hormonal contraceptives when using this medicine.

Safety Advice

sdsPregnancyUNSAFE

Can I take Cyproterone + Ethinyl Estradiol if I’m pregnant?

Cyproterone + Ethinyl Estradiol is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Cyproterone + Ethinyl Estradiol if I’m breastfeeding?

Cyproterone + Ethinyl Estradiol is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

sdsAlcoholCAUTION

Is drinking alcohol while taking Cyproterone + Ethinyl Estradiol safe?

Caution is advised when consuming alcohol with Cyproterone + Ethinyl Estradiol. Please consult your doctor.

sdsDrivingSAFE

Can I drive after taking Cyproterone + Ethinyl Estradiol?

Cyproterone + Ethinyl Estradiol does not usually affect your ability to drive.

sdsKidneyCONSULT YOUR DOCTOR

Can I take Cyproterone + Ethinyl Estradiol if I have/had kidney diseases?

There is limited information available on the use of Cyproterone + Ethinyl Estradiol in patients with kidney disease. Please consult your doctor.

sdsLiverCONSULT YOUR DOCTOR

Can I take Cyproterone + Ethinyl Estradiol if I have/had liver diseases?

There is limited information available on the use of Cyproterone + Ethinyl Estradiol in patients with liver disease. Please consult your doctor.

Frequently Asked Questions

Q. What is Cyproterone + Ethinyl Estradiol?

Cyproterone + Ethinyl Estradiol is a combination of two hormonal medicines: Cyproterone and Ethinyl Estradiol. It treats PCOS symptoms such as acne, excessive hair growth (hirsutism) and irregular periods. Cyproterone works by blocking the overproduction of androgens (male hormones) in the ovaries, thereby reducing unwanted hair growth and acne. Ethinyl Estradiol enhances the effect of Cyproterone by reducing the amount of androgens in the blood circulation.

Q. How and in what dose should I take Cyproterone + Ethinyl Estradiol?

Cyproterone + Ethinyl Estradiol has to be started on day 1 or 2 of your menstrual cycle. Take it as per the duration advised by your doctor. However, it is recommended to take it at the same time of each day. This will ensure consistent levels of medicine in your body.

Q. What if I miss a dose of Cyproterone + Ethinyl Estradiol?

If you miss a dose, you should take it as soon as possible. If the dose was missed by more than 12 hours, you should not take the missed dose and simply continue the usual dosing schedule. However, to prevent pregnancy another non- hormonal birth control (like condoms) method should be used during this cycle. Frequent missing of doses, may also cause unexpected vaginal bleeding or spotting (blood stain). If it lasts long, consult your doctor.

Q. What if I vomit after few hours of taking Cyproterone + Ethinyl Estradiol?

If vomiting occurs within 3-4 hours of taking the tablet, you must repeat the dose.

Q. Does Cyproterone + Ethinyl Estradiol also work as a contraceptive?

Yes, if taken as advised, Cyproterone + Ethinyl Estradiol also acts as a contraceptive. Discontinue using any other birth control pill while taking Cyproterone + Ethinyl Estradiol.

Q. What are the common side effects of taking Cyproterone + Ethinyl Estradiol?

The most common side effects associated with Cyproterone + Ethinyl Estradiol are nausea, stomach pain, increased weight, headache, altered mood, and breast pain. Most of these symptoms are temporary. However, if they persist, check with your doctor as soon as possible.

Q. How long will Cyproterone + Ethinyl Estradiol take to reduce acne?

Usually, you will be able to notice improvements within 3-4 weeks. However, it is important to finish the full course of treatment to see its full benefit. Inform your doctor if your acne did not get cured even after finishing the full course of treatment.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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