Clonazepam + Paroxetine

Introduction To Clonazepam + Paroxetine

Clonazepam + Paroxetine is a prescription medicine used to treat depression. It is a combination medicine which works by increasing the level of chemical messengers in the brain that improves mood. It also calms the brain by decreasing the abnormal and excessive activity of the nerve cells.

Clonazepam + Paroxetine can be taken with or without food. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. Take this medicine in the dose and duration advised by your doctor as it has habit-forming potential. Try to never skip any doses, but if you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may result in withdrawal symptoms.

Some common side effects of this medicine include nausea, vomiting, confusion, memory impairment, low sexual desire, confusion, and delayed ejaculation. It may cause dizziness and sleepiness. So, do not drive or do anything that requires mental focus until you know how this medicine affects you. It is important to inform your doctor if you develop any unusual changes in mood or depression as this medicine may cause suicidal thoughts.

Take caution while taking medicine if you are suffering from liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Uses of Clonazepam + Paroxetine

  • Depression

Benefits of Clonazepam + Paroxetine

Depression
Clonazepam + Paroxetine works by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, helps you sleep better, and increase your energy level. It is an effective antidepressant but may cause drowsiness. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

Side effects of Clonazepam + Paroxetine

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pexep Plus

  • Nausea
  • Vomiting
  • Diarrhea
  • Confusion
  • Memory impairment
  • Uncoordinated body movements
  • Drowsiness
  • Tiredness
  • Anorgasmia (decreased orgasm)
  • Low sexual desire
  • Delayed ejaculation

How to use Clonazepam + Paroxetine

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Clonazepam + Paroxetine may be taken with or without food, but it is better to take it at a fixed time.

How Clonazepam + Paroxetine works

Clonazepam + Paroxetine is a combination of two medicines: Paroxetine and Clonazepam which has mood-enhancing and anxiety-lowering effects. Paroxetine is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood. Clonazepam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain.

Quick tips

  • Clonazepam + Paroxetine is prescribed for the treatment of depression.
  • It is better to take it with a snack or just after eating breakfast, as this will help to reduce the likelihood of you feeling sick as a side-effect.
  • It can take a week or two after starting this treatment before the effect begins to build up, and 4-6 weeks before you feel the full benefit. Do not stop taking it after a week or two, feeling it is not helping.
  • Avoid taking antacids 2 hours before or after taking Clonazepam + Paroxetine as they make it harder for your body to absorb the medicine.
  • Inform your doctor immediately if you get thoughts about harming yourself or ending your life.
  • If you have diabetes, you will be asked to monitor your blood glucose level regularly as this medicine may affect the levels of sugar in your blood.
  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.

Safety Advice

sdsPregnancyUNSAFE

Can I take Clonazepam + Paroxetine if I’m pregnant?

Clonazepam + Paroxetine is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Clonazepam + Paroxetine if I’m breastfeeding?

Clonazepam + Paroxetine is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Clonazepam + Paroxetine safe?

It is unsafe to consume alcohol with Clonazepam + Paroxetine.

sdsDrivingUNSAFE

Can I drive after taking Clonazepam + Paroxetine?

Clonazepam + Paroxetine may cause side effects which could affect your ability to drive.

sdsKidneySAFE IF PRESCRIBED

Can I take Clonazepam + Paroxetine if I have/had kidney diseases?

Clonazepam + Paroxetine is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Clonazepam + Paroxetine may not be needed in these patients. Please consult your doctor. Use of Clonazepam + Paroxetine can cause excessive sleepiness in patients with end stage kidney disease.

sdsLiverCAUTION

Can I take Clonazepam + Paroxetine if I have/had liver diseases?

Clonazepam + Paroxetine should be used with caution in patients with liver disease. Dose adjustment of Clonazepam + Paroxetine may be needed. Please consult your doctor.

Frequently Asked Questions

Q. Are there any important warnings associated with the use of Clonazepam + Paroxetine?

Clonazepam + Paroxetine may increase the suicidal thoughts or actions in some patients, in the first few months of the treatment. Patients having mood or behavioral disorder have a high risk of suicidal thoughts and actions. You should pay close attention and report your doctor of any changes in behavior or mood. Make sure that you visit the doctor for the follow-up appointments as scheduled.

Q. Can I stop taking Clonazepam + Paroxetine when my symptoms are relieved?

No, you should continue taking Clonazepam + Paroxetine even if you feel well. If you stop Clonazepam + Paroxetine suddenly, serious withdrawal symptoms may occur. Your doctor will probably decrease your dose gradually.

Q. How to manage weight gain associated with the use of Clonazepam + Paroxetine?

There are reports that suggest that the use of Clonazepam + Paroxetine can cause weight gain. If you keep good eating habits and exercise regularly, you might not gain any weight. It is important to remember that it is easier to stop weight gain than losing increased weight.

Q. Can the use of Clonazepam + Paroxetine cause sleepiness?

Yes, Clonazepam + Paroxetine can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Clonazepam + Paroxetine affect my sex life?

The use of Clonazepam + Paroxetine can affect the sexual life of both men and women. Different sexual problems can occur due to Clonazepam + Paroxetine like decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort during intercourse. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Clonazepam + Paroxetine?

No, do not drink alcohol while taking Clonazepam + Paroxetine. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Clonazepam + Paroxetine.

Q. How long does Clonazepam + Paroxetine take to work?

Everybody responds differently to treatment. In general, it can take several weeks to feel the full benefits of Clonazepam + Paroxetine, although some people may start to feel better sooner. When taking Clonazepam + Paroxetine, it is important to give it time to work.

Q. What are the instructions for the storage and disposal of Clonazepam + Paroxetine?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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