Clindamycin + Isotretinoin

Clindamycin + Isotretinoin is a combination medicine that is used to treats acne. It minimizes excessive oil production, thus reduces inflammation. It also prevents the growth of the microorganisms that cause acne. This also helps to prevent pimples, blackheads, and whiteheads on the skin.

Clindamycin + Isotretinoin is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.

This is usually a safe medicine, however, it may cause dryness, peeling, redness, and burning sensation at the application site. These side effects are usually mild and self-limiting. Most of these side effects can be prevented by using a skin moisturizer and drinking plenty of water. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).

Before using this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should use this medicine with proper consultation and caution. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. During the course of the treatment, do not touch, prick or scratch the infected skin areas as this may worsen or spread the acne. Avoid unnecessary sun exposure and use a sunscreen before stepping out in the sun. It is also advised, not to receive any cosmetic procedures without asking your doctor.

• Treatment of Acne

Treatment of Acne
Clindamycin + Isotretinoin helps treat and control acne or pimples. It has a mild drying effect that reduces excess oil production in the face. This helps to unblock pores and prevent further acne breakouts. It also kills and stops the growth of bacteria causing acne. Clindamycin + Isotretinoin usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. Using this medicine will help improve your mood and uplift your confidence as acne reduces.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Clim-IT

• Skin peeling
• Itching
• Stinging sensation
• Erythema (skin redness)
• Burning sensation at the site of application

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

Clindamycin + Isotretinoin is a combination of two medicines: Clindamycin and Isotretinoin which treat pimples (acne). Clindamycin is an antibiotic which works by penetrating into the skin and killing acne-causing bacteria. Isotretinoin is a form of vitamin A. It works by reducing oil production in the skin, replenishes acne-prone skin and helps keep your pores open.

• It may take several weeks to show its action. Keep using it as suggested by your doctor.
• Wash your skin with a mild cleanser and pat it dry before applying Clindamycin + Isotretinoin.
• Apply it as a thin layer onto a clean, dry, unbroken infected area of skin.
• It may cause minor burning, stinging or irritation when applied. Inform your doctor if this does not go away.
• Avoid contact with your eyes, nose or mouth. Rinse it off with water if you accidentally get the cream in these areas.
• Use moisturizer regularly to overcome the skin dryness during the course of treatment.

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Isotretinoin. Uxbridge Middlesex: GlaxoSmithKline UK Limited; 2005 [revised 17 Sep. 2018]. [Accessed 03 Apr. 2019] (online) Available from: