Chlorzoxazone + Ibuprofen

Chlorzoxazone + Ibuprofen is a combination of two medicines used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.

Chlorzoxazone + Ibuprofen should be taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Some of the common side effects of this medicine include nausea, indigestion, heartburn, stomach pain, weakness, sleepiness, and dizziness. If any of these side effects bother you or do not go away with time, you should let your doctor know. Your doctor may help with ways to reduce or prevent these side effects.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any problems with your heart, kidneys, and liver. To make sure it is safe for you, let your doctor also know all the other medicines you are taking. Pregnant and breastfeeding mothers should consult their doctors before using this medicine as it may cause harm to the developing baby.

• Pain due to muscle spasm

Pain due to muscle spasm
Chlorzoxazone + Ibuprofen treats pain due to muscle spasm by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether, it helps in easy movement and reduces discomfort. Take this medicine by mouth with or without food as directed by your doctor. Do not increase your dose or use Chlorzoxazone + Ibuprofen more often or for longer than prescribed. Once you see some improvement, you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly. Talk to your doctor about how much exercise is good for you.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zondel

• Nausea
• Indigestion
• Heartburn
• Stomach pain
• Weakness
• Sleepiness
• Dizziness

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Chlorzoxazone + Ibuprofen is to be taken with food.

Chlorzoxazone + Ibuprofen is a combination of two medicines: Ibuprofen and Chlorzoxazone which relieve pain and relax the muscles. Ibuprofen is a non-steroidal anti- inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Chlorzoxazone is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

• You have been prescribed Chlorzoxazone + Ibuprofen to get relief from pain and stiffness in the muscles.
• Along with taking it, your doctor might advise you to undergo physiotherapy to get relief from pain.
• You might experience nausea, ask your doctor to prescribe you an antiemetic (anti-sickness medicine) if it troubles you.
• Immediately seek medical help if you experience hallucinations, sweating, shivering, fast heart rate, muscle twitching, or loss of coordination.
• Inform your doctor if you have a history of seizures, heart disease, or stroke.
• Stop using this medicine and check with your doctor right away if you are having more than one of these symptoms: abdominal pain, clay-colored stools, dark urine, fever, itching, loss of appetite, tiredness, or yellow eyes or skin.

MedIndia. Chlorzoxazone. [Accessed 22 Apr. 2019] (online) Available from:

Chlorzoxazone. Janssen Pharmaceutica (Pty) Ltd.; 1983. [Accessed 22 Apr. 2019] (online) Available from: