Bromocriptine + Metformin

Introduction To Bromocriptine + Metformin

Bromocriptine + Metformin is a combination of two medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes. It helps to maintain blood sugar levels and reduces the chances of developing serious complications of diabetes.

Bromocriptine + Metformin also helps to treat infertility, high prolactin levels and acromegaly (a hormonal disorder in which the pituitary gland produces an excess of growth hormone). It should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Bromocriptine + Metformin is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include nausea, loss of appetite, taste changes, diarrhea, dizziness, and fatigue. Some people may find that they put on weight with this medicine.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding.

Uses of Bromocriptine + Metformin

  • Treatment of Type 2 diabetes mellitus

Benefits of Bromocriptine + Metformin

Treatment of Type 2 diabetes mellitus
Bromocriptine + Metformin is a medicine that helps to control high blood glucose (sugar) levels. It helps get rid of extra glucose from your body through urine. It also improves the body’s response to the hormone insulin, which is responsible for regulating blood glucose (sugar) levels in our body. The insulin helps to lower your blood glucose levels and prevents them from rising after taking meals. You should keep taking it for as long as it is prescribed.
Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Taking this medicine regularly along with proper diet and exercise will help you live a normal, healthy life.

Side effects of Bromocriptine + Metformin

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Diacriptin M

  • Nausea
  • Loss of appetite
  • Taste change
  • Diarrhea
  • Dizziness
  • Fatigue
  • Hypoglycemia (low blood glucose level)

How to use Bromocriptine + Metformin

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bromocriptine + Metformin is to be taken with food.

How Bromocriptine + Metformin works

Bromocriptine + Metformin is a combination of two medicines: Bromocriptine and metformin.Bromocriptine is a dopamine agonist which lowers the elevated dopamine (chemical messenger in brain) levels. This reduces glucose production in the liver and lowers blood glucose levels. Metformin is a biguanide which decreases the production and absorption of glucose in your body and allows better use of existing insulin. Together, they provide better control of blood sugar.

Quick tips

  • Take it as per the dose and duration prescribed by your doctor.
  • Take it with the food to avoid stomach upset.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Avoid drinking alcohol while taking Bromocriptine + Metformin as it may increase the side effects.
  • It may cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremor, and anxiety.
  • Monitor your blood sugar level regularly while taking this medicine.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety Advice

sdsPregnancySAFE IF PRESCRIBED

Can I take Bromocriptine + Metformin if I’m pregnant?

Bromocriptine + Metformin is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Bromocriptine + Metformin if I’m breastfeeding?

Bromocriptine + Metformin is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. Bromocriptine + Metformin is usually not used during breastfeeding because it suppresses lactation.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Bromocriptine + Metformin safe?

It is unsafe to consume alcohol with Bromocriptine + Metformin.

sdsDrivingCAUTION

Can I drive after taking Bromocriptine + Metformin?

Bromocriptine + Metformin may cause dizziness or weakness due to low blood pressure. Do not drive if these symptoms occur.

sdsKidneySAFE IF PRESCRIBED

Can I take Bromocriptine + Metformin if I have/had kidney diseases?

Bromocriptine + Metformin is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Bromocriptine + Metformin may not be needed in these patients. Please consult your doctor.

sdsLiverCAUTION

Can I take Bromocriptine + Metformin if I have/had liver diseases?

Bromocriptine + Metformin should be used with caution in patients with liver disease. Dose adjustment of Bromocriptine + Metformin may be needed. Please consult your doctor. Bromocriptine + Metformin is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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