Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol

Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, throat irritation, watery eyes and congestion or stuffiness. It also helps in relieving pain and fever.

Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol is taken with or without food in a dose and duration as advised by the doctor. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are nausea, diarrhea, stomach pain, vomiting, rash, headache, anxiety, restlessness, insomnia, and increased heart rate. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine can also cause sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can make sleepiness worse.

Never support self-medication or recommend your medicine to another person. It is beneficial to have plenty of fluids while taking this medication. Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you.

• Common cold

Common cold
Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol is a combination medicine that effectively relieves symptoms of common cold such as blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps to loosen thick mucus, making it easier to cough out. This makes it easier for air to move in and out. It shrinks the blood vessels and provides rapid relief that lasts for several hours.

This medicine is safe and effective. Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol usually starts to work within a few minutes and the effects can last up to several hours. Take it as prescribed by the doctor. Do not stop using it unless you are advised to by your doctor. Taking this medicine enables you to live your life more freely without worrying so much about things that set off your symptoms.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Frekof

• Nausea
• Diarrhea
• Stomach pain
• Vomiting
• Rash
• Hives
• Allergic reaction
• Sleepiness
• Dizziness
• Headache
• Anxiety
• Restlessness
• Insomnia (difficulty in sleeping)
• Increased heart rate

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol may be taken with or without food, but it is better to take it at a fixed time.

Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol is a combination of five medicines: Guaifenesin, Bromhexine, Chlorpheniramine Maleate, Paracetamol and Ephedrine. Guaifenesin and Bromhexine help in the removal of mucus (phlegm) from the airways. Chlorpheniramine Maleate is an antiallergic which relieves allergy symptoms like runny nose, watery eyes and sneezing. Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Ephedrine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.

• Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol is prescribed to get relief from symptoms of common cold.

• Take exactly as directed by your doctor or on the label. Do not increase the dosage or take for longer than is recommended.

• Call your doctor if your symptoms have not improved within seven days of treatment.

• Inform your doctor if you are taking any other medications, e.g., anti-depressants.

• Inform your doctor if you are taking any other medications for cold.

• Along with taking Bromhexine + Chlorpheniramine Maleate + Ephedrine + Guaifenesin + Paracetamol do the following simple tips at home to get relief:

  1. Steam inhalation.
  2. Gargling with warm saltwater.
  3. Apply vapor rubs on chest, back if needed. Take enough rest.
  4. Take warm food and fluid only. Ensure adequate fluid intake.
  5. Advise hygiene measures to reduce spread: frequent hand-washing, avoiding sharing towels, pillowcase, etc.

Drugs.com. Guaifenesin. [Accessed 17 Apr. 2019] (online) Available from:

ScienceDirect. Bromhexine. [Accessed 17 Apr. 2019] (online) Available from:

Drugs.com. Chlorpheniramine Maleate. [Accessed 17 Apr. 2019] (online) Available from:

Paracetamol. Whiddon Valley: Actavis UK Limited; 1980 [revised 23 Dec. 2016]. [Accessed 18 Apr. 2019] (online) Available from:

Drugs.com. Ephedrine. [Accessed 18 Apr. 2019] (online) Available from: