Brivaracetam

Introduction To Brivaracetam

Brivaracetam is an anti-epileptic medicine used to treat seizures in epilepsy. It can be used by itself to treat adults or along with other medicines to treat adults and children. It helps to prevent seizures for as long as you continue to take it.

Brivaracetam suppresses the abnormal electrical activity in the brain. You can take it with or without food but try to take it at the same time each day to get the most benefit. The dose will depend on your condition and how you respond to the medicine. Your doctor will advise the right dose for you.

It is generally advised as a long-term treatment. You should continue taking it for as long as your doctor has told you to, even if you feel well. If you stop or miss doses your seizures could get worse. It may take several months to come off it safely. It is advisable not to change the brand of medication without doctor consultation, and always keep a stock of medicine with you.

Very few people taking it have any serious problems but the most common side effects of this medicine include sleepiness, loss of appetite, stomach pain, and diarrhea. You may also experience aggressive or abnormal behavior, depression, insomnia, dizziness, problems with balance, stomach pain, and rash. Side effects are more common during the first few weeks and usually lessen as your body gets used to the medicine. Most do not need medical attention, but some of them can be serious. Let your doctor know if you have any symptoms - there may be ways of preventing or reducing them. A small number of people being treated with this medicine have had thoughts of harming or killing themselves. Contact your doctor if your mood changes for the worse.

Before taking it, you should tell your doctor if you have kidney problems, depression or suicidal thoughts and if you are pregnant or planning to become pregnant. You should not breastfeed while taking this medicine. Alcohol may increase the risk of seizures and worsen the side effects such as drowsiness and dizziness. Avoid alcohol while taking this medicine. Drowsiness and dizziness may affect your ability to drive or operate machinery. Your kidney function may need to be tested often while taking this medicine.

Uses of Brivaracetam

  • Epilepsy/Seizures

Side effects of Brivaracetam

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Britam

  • Dizziness
  • Sedation
  • Drowsiness
  • Neuropsychiatric symptoms

How to use Brivaracetam

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Brivaracetam works

Brivaracetam is an antiepileptic medication. It works by attaching itself to specific sites (SV2A) on the surfaces of nerve cells. This suppresses the abnormal activity of the nerve cells in the brain and prevents the spread of electrical signals that cause seizures.

Quick tips

  • Brivaracetam should be taken regularly as directed by your doctor as missing doses can trigger seizures.

  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.

  • Some healthy tips to prevent seizures:

    • Take a healthy diet along with regular exercise.
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/ laptop.
    • Take your medication on time.
  • It may cause sleepiness or drowsiness. If this happens to you, do not drive or use machinery.

  • Inform your doctor if you have a history of liver disease, kidney disease or drug abuse.

  • Do not stop using Brivaracetam without talking to your doctor, even if you feel better.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Brivaracetam if I’m pregnant?

Brivaracetam may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingCONSULT YOUR DOCTOR

Can I take Brivaracetam if I’m breastfeeding?

Information regarding the use of Brivaracetam during breastfeeding is not available. Please consult your doctor.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Brivaracetam safe?

It is unsafe to consume alcohol with Brivaracetam.

sdsDrivingUNSAFE

Can I drive after taking Brivaracetam?

Brivaracetam may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

sdsKidneySAFE IF PRESCRIBED

Can I take Brivaracetam if I have/had kidney diseases?

Brivaracetam is safe to use in patients with kidney disease. No dose adjustment of Brivaracetam is recommended. Brivaracetam_name$ should not be used in end-stage renal disease, as there is no clinical study data is available to support its effect on such condition.

sdsLiverCAUTION

Can I take Brivaracetam if I have/had liver diseases?

Brivaracetam should be used with caution in patients with liver disease. Dose adjustment of Brivaracetam may be needed. Please consult your doctor.

Frequently Asked Questions

Q. Can I crush and take Brivaracetam?

No, do not crush Brivaracetam. It is recommended that you swallow the whole tablet with a glass of water. You can take Brivaracetam with or without food, preferably at the same time.

Q. What if I miss a dose of Brivaracetam?

If you have missed a dose of Brivaracetam, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose. Do not double the dose to make up for the missed one as this may increase the chances of developing side effects.

Q. Can I stop taking Brivaracetam if I start feeling better?

No, Brivaracetam should not be stopped even if you start feeling better. Suddenly stopping the medicine may cause continuous seizures which can be difficult to control. You should consult your doctor who will advise you to discontinue Brivaracetam gradually.

Q. What should I avoid while taking Brivaracetam?

Brivaracetam may cause drowsiness, tiredness, dizziness, and problems with your balance and coordination. Therefore, you should avoid driving or operating heavy machinery until you know how the medicine affects you. Also, you should avoid alcohol while taking this medicine as you may experience unwanted effects on memory and attention.

Q. What if I accidentally take more than the recommended dose of Brivaracetam?

If you take more than the recommended dose of Brivaracetam, you may experience a spinning sensation, balance disorder, fatigue, nausea, double vision, anxiety and slow heartbeat. Consult your doctor immediately if you experience any such symptoms.

Q. How can I watch for early symptoms of suicidal thoughts and actions?

You should pay attention to any changes, especially sudden changes in mood, behaviors, thoughts, or feelings. Be aware of common warning signs that might be a signal for the risk of suicide. Some of these include talking or thinking about hurting yourself or ending your life, withdrawing from friends and family, becoming depressed or worsening of your depression, or becoming preoccupied with death and dying. Never miss an appointment with your doctor and stay connected with the doctor even between visits.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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