Bisoprolol + S-Amlodipine

Bisoprolol + S-Amlodipine is a combination medicine used in the treatment of hypertension (high blood pressure). It works by relaxing the blood vessels and making the heart more efficient at pumping blood throughout the body.

You can take Bisoprolol + S-Amlodipine at any time of day, with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine.

It may cause side effects like headache, nausea, flushing (sense of warmth in the face, ears, neck and trunk), ankle swelling, and slow heart rate. It may also cause dizziness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. To reduce the swelling, raise your legs while sitting down. You may be asked for regular monitoring of blood pressure, kidney function, blood sugar level, and electrolytes level while on the treatment.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions.

• Hypertension (high blood pressure)

Hypertension (high blood pressure)
Bisoprolol + S-Amlodipine relaxes the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bisnorm

• Headache
• Nausea
• Tiredness
• Sleepiness
• Dizziness
• Slow heart rate
• Abnormal dreams
• Swelling of legs
• Cold extremities
• Flushing (sense of warmth in the face, ears, neck and trunk)
• Constipation
• Ankle swelling
• Edema (swelling)
• Palpitations

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Bisoprolol + S-Amlodipine may be taken with or without food, but it is better to take it at a fixed time.

Bisoprolol + S-Amlodipine is a combination of two medicines: S-Amlodipine and Bisoprolol which lower blood pressure effectively. S-Amlodipine is a calcium channel blocker which works by relaxing blood vessels while Bisoprolol is a beta blocker that works specifically on the heart to slow down the heart rate. Together, they make the heart more efficient at pumping blood throughout the body.

• You have been prescribed Bisoprolol + S-Amlodipine for the treatment of high blood pressure.

• Lowering blood pressure reduces chance of future heart attack & strokes.

• It may cause dizziness. Get up slowly when rising from a sitting or lying position.

• Do not stop taking the medication suddenly without talking to your doctor as it can cause sudden increase in your blood pressure.

• Let your doctor know if you are pregnant or planning for pregnancy.

Amlodipine besilate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2011 [revised 11 Apr. 2018]. [Accessed 25 Apr. 2019] (online) Available from:

Drugs.com. Bisoprolol. [Accessed 25 Apr. 2019] (online) Available from: