Artesunate + Pyrimethamine + Sulphadoxine

Artesunate + Pyrimethamine + Sulphadoxine is a combination medicine that is prescribed to treat malaria. It fights against the infection by preventing the growth of the parasites inside the body.

Artesunate + Pyrimethamine + Sulphadoxine is a prescription medicine. It is to be taken with food and take it at a fixed time regularly. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. A missed dose should be taken as soon as you remember. The course of the treatment should be completed for better efficacy.

While on this medicine, some people may experience weakness, nausea, headache, mouth sore, etc. as its side effects. Please consult your doctor if these side effects persist for a longer duration.

Before using it, you should tell your doctor if you are allergic to any antibiotics (especially sulpha medicines) or have any kidney or liver problems. Pregnant and breastfeeding mothers should consult their doctor before taking this medicine. Your doctor may monitor you with regular blood and urine tests during treatment.

• Treatment of Malaria

Treatment of Malaria
Malaria is a serious or life-threatening illness that is spread by a parasite that enters the human body by the bite of infected mosquitoes. Artesunate + Pyrimethamine + Sulphadoxine is an antimalarial medicine and is used to treat malaria. It kills the infection- causing parasite and stops the further spread of the infection in the body. Do not use this medicine for treating any other condition without consulting your doctor.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Aight SP

• Nausea
• Vomiting
• Diarrhea
• Feeling of fullness
• Mouth sore
• Skin rash
• Fatigue
• Headache
• Dizziness
• Upset stomach
• ECG changes

Take this medicine in the dose and duration as advised by your doctor. Check the label before use. Artesunate + Pyrimethamine + Sulphadoxine is to be taken with food.

Artesunate + Pyrimethamine + Sulphadoxine is a combination of three medicines: Artesunate, Sulphadoxine and Pyrimethamine which treat malaria. Artesunate and Pyrimethamine are antiparasitic medicines which work by increasing the levels of haeme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading. Sulphadoxine is an antibiotic which stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.

• Artesunate + Pyrimethamine + Sulphadoxine is prescribed for the treatment of malaria.

• It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.

• It may cause dizziness. Do not drive or do anything that requires mental focus until you know how the medicine affects you.

• Artesunate + Pyrimethamine + Sulphadoxine should be taken with food or drinks enriched with fat such as milk.

• Inform your doctor if you have anemia.

• Inform your doctor if you notice flu-like symptoms such as chills, fever, muscle pains, and any changes in a heartbeat.

• You may be asked for a regular blood test once a week while taking this medicine.

Artesunate+Sulfadoxine/Pyrimethamine [Patient Information Leaflet]. Guilin, China: Guilin Pharmaceutical Co. Ltd.; 2016. [Accessed 17 Feb. 2020] (online) Available from:

Maiga H, Djimde AA, Beavogui AH, et al. Efficacy of sulphadoxine-pyrimethamine + artesunate, sulphadoxine-pyrimethamine + amodiaquine, and sulphadoxine-pyrimethamine alone in uncomplicated falciparum malaria in Mali. Malar J. 2015;14:64. [Accessed 17 Feb. 2020] (online) Available from:

Priotto G, Kabakyenga J, Pinoges L, et al. Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial. Trans R Soc Trop Med Hyg. 2003;97(3):325-30. [Accessed 17 Feb. 2020] (online) Available from: