Amlodipine + Chlorthalidone

Introduction To Amlodipine + Chlorthalidone

Amlodipine + Chlorthalidone is a combination medicine used in the treatment of hypertension (high blood pressure). It also helps to reduce the risk of stroke and heart attack. It should be taken in the morning with food to avoid frequent urination at night.

Amlodipine + Chlorthalidone should be taken with food preferably in the morning to avoid frequent urination at night. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Keeping active with regular exercise, reducing your weight and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine.

Glucose intolerance, ankle swelling, headache, and decreased potassium level are some common side effects of this medicine. Consult your doctor If any of these bother you, or get worse, or do not go away. Drink plenty of fluids while taking medicine to overcome muscle weakness, dry mouth, and extreme thirst. Dizziness or headache may occur due to low blood pressure, hence rise slowly from sitting position or avoid driving.

Before taking it, let your doctor know if you have any liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking especially those used to treat high blood pressure or heart conditions. You should have your blood pressure, kidney function, level of electrolytes, and blood sugar level checked regularly to make sure that this medicine is working properly.

Uses of Amlodipine + Chlorthalidone

  • Hypertension (high blood pressure)

Benefits of Amlodipine + Chlorthalidone

Hypertension (high blood pressure)
Amlodipine + Chlorthalidone relaxes the blood vessels so that blood can flow more easily around your body. It also eliminates excess water from the body and increases urine output. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. You should take it regularly as prescribed for this medicine to be most effective, even if you feel better.

Side effects of Amlodipine + Chlorthalidone

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Enzochlor

  • Glucose intolerance
  • Sleepiness
  • Ankle swelling
  • Headache
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Tiredness
  • Palpitations
  • Nausea
  • Increased blood uric acid
  • Decreased potassium level in blood
  • Altered blood lipid level

How to use Amlodipine + Chlorthalidone

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amlodipine + Chlorthalidone is to be taken with food.

How Amlodipine + Chlorthalidone works

Amlodipine + Chlorthalidone is a combination of two medicines: Amlodipine and chlorthalidone which lower blood pressure effectively. Amlodipine is a calcium channel blocker which relaxes blood vessels and makes the heart more efficient at pumping blood throughout the body. Chlorthalidone is a diuretic which removes extra water and certain electrolytes from the body by increasing the amount of urine produced. Over time it also works by relaxing blood vessels and improving blood flow.

Quick tips

  • Amlodipine + Chlorthalidone helps in the treatment of high blood pressure.
  • It also lowers your risk of stroke and heart attack.
  • Take it in the morning with breakfast to avoid getting up at night to urinate.
  • It may cause dizziness or sleepiness. Don't drive or do anything requiring concentration until you know how it affects you.
  • It may cause you to feel lightheaded or weak especially when you stand up (orthostatic hypotension). Rise slowly if you have been sitting or lying down.
  • It may cause dehydration. Drink plenty of fluids and Inform your doctor if you develop extreme thirst, muscle weakness or very dry mouth.
  • Your doctor may regularly monitor your blood pressure, kidney function and the levels of salts such as potassium in your blood while you are taking this medicine.

Safety Advice

sdsPregnancyCONSULT YOUR DOCTOR

Can I take Amlodipine + Chlorthalidone if I’m pregnant?

Amlodipine + Chlorthalidone may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

sdsBreastfeedingSAFE IF PRESCRIBED

Can I take Amlodipine + Chlorthalidone if I’m breastfeeding?

Amlodipine + Chlorthalidone is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

sdsAlcoholUNSAFE

Is drinking alcohol while taking Amlodipine + Chlorthalidone safe?

It is unsafe to consume alcohol with Amlodipine + Chlorthalidone.

sdsDrivingUNSAFE

Can I drive after taking Amlodipine + Chlorthalidone?

Amlodipine + Chlorthalidone may cause side effects which could affect your ability to drive. Amlodipine + Chlorthalidone may cause side effects such as dizziness, headaches, nausea or tiredness, all of which could affect your ability to concentrate and drive.

sdsKidneyCAUTION

Can I take Amlodipine + Chlorthalidone if I have/had kidney diseases?

Amlodipine + Chlorthalidone should be used with caution in patients with severe kidney disease. Dose adjustment of Amlodipine + Chlorthalidone may be needed. Please consult your doctor. Use of Amlodipine + Chlorthalidone is not recommended in these patients.

sdsLiverCAUTION

Can I take Amlodipine + Chlorthalidone if I have/had liver diseases?

Amlodipine + Chlorthalidone should be used with caution in patients with liver disease. Dose adjustment of Amlodipine + Chlorthalidone may be needed. Please consult your doctor. Use of Amlodipine + Chlorthalidone is not recommended in patients with severe liver disease.

References

Written By:

Dr Advikka Ridhy

Dr Advikka Ridhy

MBBS

RMO, Aster MIMS

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