Amitriptyline + Propranolol

Amitriptyline + Propranolol is a combination of two medicines used in the treatment of migraine. It works by increasing the levels of chemical messengers in the brain that help in relieving pain sensation. It also helps in elevating your mood and relaxes the nerves in the brain.

Amitriptyline + Propranolol should be taken on an empty stomach. However, it is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you have missed any dose, take it as soon as you remember. Never skip any doses and finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly as it may worsen your symptoms.

Some common side effects of this medicine include sedation, fatigue, slow heart rate, insomnia (difficulty in sleeping), tiredness, blurred vision, dryness in mouth, difficulty in urination, constipation, nightmares, and cold extremities. It may cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. However, these are temporary and usually resolve on their own. Please consult your doctor if these do not subside or bother you.

You should avoid alcohol while taking Amitriptyline + Propranolol, as it may worsen certain side effects. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

• Migraine

Migraine
Amitriptyline + Propranolol helps treat migraine by changing the way that your nerves receive pain signals. This helps you relax, feel calm, more energetic and also helps you concentrate better. By managing and reducing the frequency of headaches, it can help you carry out your daily activities and have a better quality of life.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Amnurite Beta

• Sedation
• Weight gain
• Fatigue
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Slow heart rate
• Insomnia (difficulty in sleeping)
• Tiredness
• Blurred vision
• Dryness in mouth
• Difficulty in urination
• Constipation
• Nightmares
• Cold extremities

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amitriptyline + Propranolol is to be taken empty stomach.

Amitriptyline + Propranolol is a combination of two medicines. Amitriptyline is a is a tricyclic antidepressant. It also stops the movement of pain signals from nerves to the brain thereby relieving pain. Propranolol is a beta blocker. It also widens the blood vessels in the body for better blood flow. This is how Amitriptyline + Propranolol treats migraine.

• Amitriptyline + Propranolol helps to ease the pain you feel during a migraine headache.
• This medicine can only decrease the number and severity of attacks but may not completely stop them.
• Do not take any other pain killer without consulting your doctor.
• Some tips that may help avoid a migraine attack:

a) Have your meals at the same time every day.

b) Avoid bright lights and extreme temperatures.

c) Avoid loud music and noisy places.

d) Avoid chocolates, cheese, processed food, alcohol, and smoking.

f) Get sufficient sleep and avoid stress.

Amitriptyline. Princeton, New Jersey: Sandoz Inc.; 2014. [Accessed on 19 Mar. 2019] (online) Available from:

Propranolol. Barnstaple, Devon: Actavis; 2018. [Accessed 20 Mar. 2019] (online) Available from: