Amitriptyline

Amitriptyline contains amitriptyline, an antidepressant used to treat moderate to severe depression, panic disorders and chronic pain syndromes like migraines and nerve damage. This medication works by altering the levels of neurotransmitters in our brain and blocking specific receptors in our body. It treats symptoms like low mood, fatigue, anxiety, hopelessness, headaches, neuropathic pain, etc.

Amitriptyline should be taken as advised by your doctor; the dose may be adjusted depending on the severity of your clinical symptoms. You may take this medicine before or after food, ideally at the same time each day. Follow your doctor's orders, and don't stop taking the medicine until they tell you to; stopping it suddenly can lead to withdrawal symptoms.

Side effects of Amitriptyline include nausea, vomiting, dry mouth, blurred vision, excessive sweating, changes in appetite and sex drive, drowsiness and nightmares. These adverse effects usually go away on their own - talk to your doctor if they persist or become severe.

Amitriptyline is contraindicated (unsafe) for people with a history of heart attacks, bipolar illness and hypersensitivity to amitriptyline. Do not take this medicine if you’re already taking cisapride (gastroprokinetic agent) or antidepressants called monoamine oxidase inhibitors. Always let your doctor know of any health conditions you might have.

Amitriptyline is used to reduce symptoms related to depression and chronic pain conditions. It alters the levels of neurotransmitters and blocks specific receptors in the body, which helps alleviate symptoms like low mood, fatigue, trembling, racing heartbeat, feeling of hopelessness, headaches and nerve pain.

Amitriptyline contains amitriptyline, a tricyclic antidepressant. It is used in the treatment of the following conditions:

Amitriptyline contains amitriptyline, which works by altering the levels of neurotransmitters in our brain and blocking certain receptors in our body. It treats symptoms like low mood, fatigue, anxiety, feeling of hopelessness, headaches, neuropathic pain conditions, etc.

This tricyclic antidepressant (TCA) medicine blocks or inhibits the neuronal absorption/reuptake of neurotransmitters like norepinephrine and serotonin into the end of the nerve cell called presynaptic nerve terminals. This, in turn, blocks the removal of the neurotransmitters, thereby increasing the concentrations of monoamines in the space between two nerve cells called the synaptic cleft. This process results in the antidepressant effect that the medicine provides.

Amitriptyline also blocks serotonergic, adrenergic, histaminic, and muscarinic receptors, which leads to common side effects such as blurred vision, dry mouth and constipation.

• Amitriptyline (medlineplus.gov)
• Amitriptyline overview (ncbi.nlm.nih.gov)